Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20758546 | 0.80 | KIF11 (0.49) | KIF11KDM1ANPFFR1NPFFR2CYP11B1 | |
| SCHEMBL8604005 | 0.74 | NPC1 (0.55) | KIF11NPFFR1NPFFR2CYP11B1CYP11B2 | |
| SCHEMBL8154205 | 0.74 | NPC1 (0.55) | KIF11NPFFR1NPFFR2CYP11B1CYP11B2 | |
| SCHEMBL20740835 | 0.73 | KIF11 (0.56) | KIF11KDM1ACYP11B1CYP11B2 | |
| SCHEMBL22915185 | 0.71 | GRIN2D (0.42) | — | |
| SCHEMBL14333733 | 0.71 | KIF11 (0.41) | KIF11KDM1ANPFFR1NPFFR2CYP11B1 | |
| SCHEMBL7789065 | 0.71 | KIF11 (0.41) | KIF11NPFFR1NPFFR2 | |
| SCHEMBL14333738 | 0.71 | KIF11 (0.41) | KIF11KDM1ANPFFR1NPFFR2CYP11B1 | |
| SCHEMBL7788488 | 0.71 | CYP11B1 (0.50) | KIF11CYP11B1CYP11B2 | |
| SCHEMBL14333735 | 0.71 | KIF11 (0.41) | KIF11KDM1ANPFFR1NPFFR2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3770146-A1 | PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | Mitobridge, Inc. (US) | 2021-01-27 | — | — | EP | disclosed |