Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21236969 | 0.85 | NPFFR1 (0.40) | KIF11NPFFR1NPFFR2 | |
| SCHEMBL22915197 | 0.80 | KIF11 (0.44) | KIF11KDM1ANPFFR1NPFFR2CYP11B1 | |
| SCHEMBL8154205 | 0.80 | NPC1 (0.55) | KIF11NPFFR1NPFFR2CYP11B1CYP11B2 | |
| SCHEMBL8604005 | 0.80 | NPC1 (0.55) | KIF11NPFFR1NPFFR2CYP11B1CYP11B2 | |
| SCHEMBL20740835 | 0.78 | KIF11 (0.56) | KIF11KDM1ACYP11B1CYP11B2 | |
| SCHEMBL22550282 | 0.78 | NFE2L2 (0.50) | — | |
| SCHEMBL7788488 | 0.76 | CYP11B1 (0.50) | KIF11CYP11B1CYP11B2 | |
| SCHEMBL14333738 | 0.76 | KIF11 (0.41) | KIF11KDM1ANPFFR1NPFFR2CYP11B1 | |
| SCHEMBL14333733 | 0.76 | KIF11 (0.41) | KIF11KDM1ANPFFR1NPFFR2CYP11B1 | |
| SCHEMBL14333735 | 0.76 | KIF11 (0.41) | KIF11KDM1ANPFFR1NPFFR2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190053492-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2019-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190053492-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS PESTICIDES | CHRM1, CHRM2, ACHE | KIF11 3107/4885KDM1A 553/4885NPFFR1 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.