Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | NQO2 | P16083 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridine SCHEMBL5192718 | 0.86 | ALDH1A1 (0.65) | MAPTNQO2KDM4EALDH1A1POLB | |
| Naphthalene SCHEMBL1829374 | 0.80 | CYP2A6 (0.50) | KDM4EALDH1A1HPGDGAALMNA | |
| Quinoxaline SCHEMBL1259050 | 0.80 | ALDH1A1 (0.41) | MAPTKDM4EALDH1A1POLBNPC1 | |
| Ether SCHEMBL16742369 | 0.80 | ALDH1A1 (0.49) | MAPTKDM4EALDH1A1NPC1HPGD | |
| Quinoline SCHEMBL1257445 | 0.78 | ALDH1A1 (0.68) | MAPTKDM4EALDH1A1POLBNPC1 | |
| Naphthalene SCHEMBL8526780 | 0.78 | CYP2A6 (0.47) | KDM4EALDH1A1HPGDGAALMNA | |
| Phenazine SCHEMBL28805065 | 0.78 | MAPT (0.65) | MAPTNQO2KDM4EALDH1A1POLB | |
| Phenanthrene SCHEMBL27863132 | 0.77 | ALDH1A1 (0.60) | MAPTKDM4EALDH1A1HPGDLMNA | |
| Phenazine SCHEMBL9049 | 0.76 | MAPT (1.00) | MAPTNQO2KDM4EALDH1A1POLB | |
| Phenazine SCHEMBL29356959 | 0.76 | MAPT (1.00) | MAPTNQO2KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265726-B1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | ROCHE DIAGNOSTICS GMBH (DE) | 2014-05-07 | — | — | EP | disclosed |
| US-8535511-B2 | Methods for electrochemical analysis using matrix compositions with alkylphenazine quaternary salt and a nitrosoaniline | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-8008037-B2 | Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| EP-2265726-A1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | Roche Diagnostics GmbH (DE) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009118157-A1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | ROCHE DIAGNOSTICS GMBH (DE) | 2009-10-01 | — | — | WO | disclosed |
| US-20090246808-A1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | ROCHE DIABETES CARE, INC. | 2009-10-01 | — | — | US | disclosed |