Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL1257445 | 0.83 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTNPC1NCF1 | |
| Phenazine SCHEMBL2291612 | 0.80 | MAPT (0.58) | ALDH1A1KDM4EMAPTNPC1NCF1 | |
| Quinoxaline SCHEMBL19877227 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTNPC1NCF1 | |
| Quinoxaline SCHEMBL5315 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTNCF1MEN1 | |
| Quinoxaline SCHEMBL6928518 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTNCF1MEN1 | |
| Quinoxaline SCHEMBL29355228 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTNCF1MEN1 | |
| Quinoxaline SCHEMBL30320908 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTNCF1MEN1 | |
| Ether SCHEMBL2007543 | 0.78 | LOXL2 (0.46) | ALDH1A1KDM4EMAPTNPC1NCF1 | |
| Quinoxaline SCHEMBL27924506 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTNPC1NCF1 | |
| Quinoxaline SCHEMBL27596038 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTNPC1NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130224624-A1 | PROTON EXCHANGE MEMBRANES | RENO (US) | 2013-08-29 | — | — | US | claimed |
| US-8071710-B2 | Thermoplastic polyphenoxyquinoxaline and method of preparing the same | THE UNIVERSITY OF AKRON (US) | 2011-12-06 | — | — | US | claimed |
| US-20110033776-A1 | PROTON EXCHANGE MEMBRANES | Board of regents of the Nevada System of Higher Education, on Behalf of the University of | 2011-02-10 | — | — | US | claimed |
| US-20100048857-A1 | THERMOPLASTIC POLYPHENOXYQUINOXALINE AND METHOD OF PREPARING THE SAME | THE UNIVERSITY OF AKRON (US) | 2010-02-25 | — | — | US | claimed |
| US-20040102584-A1 | Low dielectric constant materials with polymeric networks | LAU KREISLER S (US) | 2004-05-27 | — | — | US | claimed |
| US-6713590-B2 | FABRICATED FROM FIRST COMPONENT COMPRISING POLYMERIC STRAND AND SECOND COMPONENT COMPRISING MOLECULE HAVING CENTRAL PORTION WITH AT LEAST THREE ARMS EXTENDING THEREFROM | HONEYWELL INTERNATIONAL INC. | 2004-03-30 | — | — | US | claimed |
| EP-1303550-A4 | LOW DIELECTRIC CONSTANT MATERIALS WITH POLYMERIC NETWORKS | HONEYWELL INT INC (US) | 2003-07-30 | — | — | EP | claimed |
| EP-1303550-A1 | LOW DIELECTRIC CONSTANT MATERIALS WITH POLYMERIC NETWORKS | Honeywell International, Inc. (US) | 2003-04-23 | — | — | EP | claimed |
| US-6423811-B1 | ACETYLENIC COPOLYMERS; INTERPENETRATING POLYMER NETWORK | HONEYWELL INTERNATIONAL INC. | 2002-07-23 | — | — | US | claimed |
| US-20020037941-A1 | Low dielectric constant materials with polymeric networks | LAU KREISLER S (US) | 2002-03-28 | — | — | US | claimed |
| WO-2002006366-A1 | LOW DIELECTRIC CONSTANT MATERIALS WITH POLYMERIC NETWORKS | HONEYWELL INTERNATIONAL INC. (US) | 2002-01-24 | — | — | WO | claimed |
| EP-3071582-B1 | MITOCHONDRIA-TARGETED DICARBONYL SEQUESTERING COMPOUNDS | RES & INNOVATION UK (GB) | 2020-04-29 | — | — | EP | disclosed |
| EP-3623375-A1 | MITOCHONDRIA-TARGETED DICARBONYL SEQUESTERING COMPOUNDS | United Kingdom Research and Innovation (GB) | 2020-03-18 | — | — | EP | disclosed |
| CN-105873936-B | Mitochondrially targeted dicarbonyl chelate compounds | 医药研究委员会 | 2018-09-14 | — | — | CN | disclosed |
| US-9963474-B2 | Mitochondria-targeted dicarbonyl sequestering compounds | MEDICAL RESEARCH COUNCIL (GB) | 2018-05-08 | — | — | US | disclosed |
| US-20020037941-A1 | Low dielectric constant materials with polymeric networks | LAU KREISLER S (US) | 2002-03-28 | — | — | US | disclosed |
| WO-2002006366-A1 | LOW DIELECTRIC CONSTANT MATERIALS WITH POLYMERIC NETWORKS | HONEYWELL INTERNATIONAL INC. (US) | 2002-01-24 | — | — | WO | disclosed |
| US-3956238-A | Polyetherquinoxalines | GENERAL ELECTRIC COMPANY (US) | 1976-05-11 | — | — | US | disclosed |
| US-3956238-A | Polyetherquinoxalines | GENERAL ELECTRIC COMPANY (US) | 1976-05-11 | — | — | US | disclosed |
| US-3852244-A | POLYETHERQUINOXALINES | GEN ELECTRIC | 1974-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048857-A1 | THERMOPLASTIC POLYPHENOXYQUINOXALINE AND METHOD OF PREPARING THE SAME | RECQL, BLM, RB1 | ALDH1A1 3956/4885KDM4E 408/4885MAPT 4041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.