Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL28244243 | 0.94 | ALDH1A1 (0.61) | ALDH1A1PDE10ANPC1POLBRAB9A | |
| Quinoline SCHEMBL2535469 | 0.87 | ALDH1A1 (0.81) | ALDH1A1PDE10ANPC1POLBRAB9A | |
| Quinoline SCHEMBL27960167 | 0.85 | ALDH1A1 (0.77) | ALDH1A1PDE10ANPC1POLBRAB9A | |
| Quinoline SCHEMBL4599170 | 0.85 | ALDH1A1 (0.77) | ALDH1A1PDE10ANPC1POLBRAB9A | |
| Quinoline SCHEMBL28292257 | 0.83 | ALDH1A1 (0.74) | ALDH1A1PDE10ANPC1POLBRAB9A | |
| Quinoline SCHEMBL6399465 | 0.83 | ALDH1A1 (0.74) | ALDH1A1PDE10ANPC1POLBRAB9A | |
| Quinoline SCHEMBL27849601 | 0.83 | ALDH1A1 (0.74) | ALDH1A1PDE10ANPC1POLBRAB9A | |
| Quinoline SCHEMBL4265438 | 0.83 | ALDH1A1 (0.74) | ALDH1A1PDE10ANPC1POLBRAB9A | |
| Quinoline SCHEMBL27467057 | 0.83 | ALDH1A1 (0.74) | ALDH1A1PDE10ANPC1POLBRAB9A | |
| Quinoline SCHEMBL28250556 | 0.83 | ALDH1A1 (0.74) | ALDH1A1PDE10ANPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776410-B | Heptafluoroisopropyl quinoline ether-containing compound, preparation method and application thereof | 浙江省化工研究院有限公司 | 2021-02-05 | — | — | CN | claimed |
| CN-109776410-A | A kind of ether compound of quinoline containing hepta-fluoroiso-propyl, preparation method and application | 浙江省化工研究院有限公司 | 2019-05-21 | — | — | CN | claimed |
| CN-102382484-A | Polynuclear arene photosensitive material and dye-sensitized solar cell prepared by same | UNIV CHINA PETROLEUM | 2012-03-21 | — | — | CN | claimed |
| JP-2076855-A | — | — | None | — | — | JP | disclosed |
| CN-120623147-B | Pyrazolyl quinoline ether compound and application thereof in preparation of neuroprotective drugs | 广东省科学院动物研究所 | 2025-12-16 | — | — | CN | disclosed |
| CN-120623147-A | Pyrazolyl quinoline ether compound and application thereof in preparation of neuroprotective drugs | 广东省科学院动物研究所 | 2025-09-12 | — | — | CN | disclosed |
| US-12011423-B2 | S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders | FORAVISET LTD. (IL) | 2024-06-18 | — | — | US | disclosed |
| WO-2023213740-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | PHILIP MORRIS PRODUCTS S.A. (CH) | 2023-11-09 | — | — | WO | disclosed |
| CN-113549053-B | Pyrazoloquine (azolyl) ether compound and application thereof | 沈阳中化农药化工研发有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-109776410-B | Heptafluoroisopropyl quinoline ether-containing compound, preparation method and application thereof | 浙江省化工研究院有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-111978156-A | Method for preparing cannabidiol | 云南汉盟制药有限公司 | 2020-11-24 | — | — | CN | disclosed |
| WO-1993008171-A1 | PYRIMIDOCYCLOALKANES AS ANGIOTENSIN II ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-04-29 | — | — | WO | disclosed |
| WO-1993008170-A1 | SUBSTITUTED HETEROCYCLES AS ANGIOTENSIN II ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0539086-A2 | Condensed pyrimidine derivatives and their use as angiotensine II antagonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| US-5187168-A | Hypotensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-16 | — | — | US | disclosed |
| US-5149699-A | Substituted pyridopyrimidines useful as antgiotensin II antagonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| US-5102881-A | Leukotriene biosynthesis inhibitor | MERCK FROSST CANADA, INC. (CA) | 1992-04-07 | — | — | US | disclosed |
| CN-1051359-A | Improved imidazo [4, the 5-b] quinolinyloxyalkanoic acid amides of water-soluble degree | BRISTOL MYERS SQUIBB CO (US) | 1991-05-15 | — | — | CN | disclosed |
| JP-H0276855-A | QUINOLINE ETHER ALKANOIC ACID | MERCK FROSST CANADA INC | 1990-03-16 | — | — | JP | disclosed |
| EP-0349062-A1 | Quinoline ether alkanoic acid | MERCK FROSST CANADA INC. (CA) | 1990-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12011423-B2 | S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders | KCNN3, ITPR3, KCNN2 | ALDH1A1 2043/4885PDE10A 320/4885NPC1 4310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.