Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DUT | P33316 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14476942 | 0.84 | KCNN4 (0.47) | KCNN4KIF11CYP2C19HIF1AHDAC3 | |
| SCHEMBL13865454 | 0.84 | PPID (0.55) | KCNN4POLBALDH1A1LMNAKDM4E | |
| SCHEMBL9165257 | 0.84 | DPP4 (0.49) | KCNN4POLBCES1CYP2C19HIF1A | |
| SCHEMBL9040716 | 0.82 | KIF11 (0.50) | KCNN4KIF11POLBTSHRDUT | |
| SCHEMBL4199968 | 0.82 | KCNN4 (0.56) | KCNN4KIF11CES1CYP2C19HIF1A | |
| SCHEMBL28544425 | 0.81 | KCNN4 (0.55) | KCNN4KIF11CYP2C19HIF1ADUT | |
| SCHEMBL35211130 | 0.81 | KCNN4 (0.43) | KCNN4KIF11CYP2C19HIF1ADUT | |
| SCHEMBL14356107 | 0.80 | KIF11 (0.49) | KCNN4KIF11CES1ALDH1A1LMNA | |
| SCHEMBL30610089 | 0.80 | KIF11 (0.49) | KCNN4KIF11CES1ALDH1A1LMNA | |
| SCHEMBL16427979 | 0.80 | LMNA (0.49) | KCNN4KIF11TSHRDUTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11147802-B2 | Substituted oxadiazole chemical compound and composition containing said chemical compound and use thereof | SHENZHEN TARGETRX, INC. (CN) | 2021-10-19 | — | — | US | disclosed |
| US-20210186933-A1 | SUBSTITUTED OXADIAZOLE CHEMICAL COMPOUND AND COMPOSITION CONTAINING SAID CHEMICAL COMPOUND AND USE THEREOF | SHENZHEN TARGETRX, INC. (CN) | 2021-06-24 | — | — | US | disclosed |
| EP-3398942-B1 | SUBSTITUTED OXADIAZOLE CHEMICAL COMPOUND AND COMPOSITION CONTAINING SAID CHEMICAL COMPOUND AND USE THEREOF | SHENZHEN TARGETRX INC (CN) | 2021-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11147802-B2 | Substituted oxadiazole chemical compound and composition containing said chemical compound and use thereof | IDO1, IDO2, CYP3A43 | KCNN4 3183/4885KIF11 2815/4885POLB 3458/4885 |
| US-20210186933-A1 | SUBSTITUTED OXADIAZOLE CHEMICAL COMPOUND AND COMPOSITION CONTAINING SAID CHEMICAL COMPOUND AND USE THEREOF | IDO1, IDO2, CYP3A43 | KCNN4 3183/4885KIF11 2815/4885POLB 3458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.