SCHEMBL22916733

SCHEMBL22916733

CC1(C)c2cc(-c3ccc(C#N)cc3)ccc2-c2c1cc1c3c(cccc23)-c2c-1c(-c1ccccc1)c1ccccc1c2-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.40
PGR P06401 5/20 0.39
ALDH1A1 P00352 2/20 0.36
ATM Q13315 1/20 0.36
GABRA1 P14867 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34
KAT6A Q92794 1/20 0.33
ALK Q9UM73 2/20 0.33
STK10 O94804 2/20 0.32
SLK Q9H2G2 2/20 0.32
CHEK1 O14757 1/20 0.31
PRKDC P78527 1/20 0.31
ACLY P53396 1/20 0.31
DYRK3 O43781 1/20 0.31
CLK1 P49759 1/20 0.31
CLK2 P49760 1/20 0.31
SRPK2 P78362 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21239499 0.96 PDK2 (0.38) PDK2PGRALDH1A1ATMGABRA1
SCHEMBL3222953 0.89 PDK2 (0.44) PDK2PGRALDH1A1ATMGABRA1
SCHEMBL22597479 0.84 PDK2 (0.42) PDK2PGRALDH1A1ATMGABRA1
SCHEMBL22113244 0.81
SCHEMBL25129017 0.80 PDK2 (0.39) PDK2PGRALDH1A1ATMGABRA1
SCHEMBL22597474 0.80 CHEK1 (0.31) CHEK1
SCHEMBL22597476 0.80 PLA2G2A (0.34) PGRALDH1A1
SCHEMBL25129196 0.80 PDK2 (0.32) PDK2PGR
SCHEMBL22916804 0.80 PDK2 (0.38) PDK2PGRALDH1A1ATMGABRA1
SCHEMBL22113229 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345816-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-10-26 US disclosed
US-20230345816-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-10-26 US disclosed
US-20230242465-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-08-03 US disclosed
US-11618722-B2 Compound, composition, organic electroluminescent element, and electronic appliance IDEMITSU KOSAN CO., LTD. (JP) 2023-04-04 US disclosed
US-20230047477-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-16 US disclosed
US-20230042023-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-09 US disclosed
US-11552252-B1 2023-01-10 US disclosed
US-20220285625-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-09-08 US disclosed
WO-2021107030-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2021-06-03 WO disclosed
US-20210028365-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO.,LTD. (JP) 2021-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242465-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE EP300, RPS19, RER1 PDK2 2873/4885PGR 2422/4885ALDH1A1 2901/4885
US-11618722-B2 Compound, composition, organic electroluminescent element, and electronic appliance FGF23, SUZ12, RPL24 PDK2 4233/4885PGR 3984/4885ALDH1A1 3606/4885
US-20230345816-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE LEF1, L1CAM, YBX1 PDK2 1014/4885PGR 1822/4885ALDH1A1 2247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.