SCHEMBL22916772

SCHEMBL22916772

CCCCC#Cc1cc(C(C)(C)C)ccc1C(=O)C(=O)OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPT P10636 1/20 0.37
APEX1 P27695 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CTSL P07711 1/20 0.36
CTSB P07858 1/20 0.36
HDAC3 O15379 2/20 0.35
HDAC1 Q13547 2/20 0.35
HDAC2 Q92769 2/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
NR1H4 Q96RI1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22916780 0.85 CYP3A4 (0.36) CYP3A4CYP2C9CYP2C19KDM4ELMNA
SCHEMBL5667707 0.76 TDP1 (0.41) CYP3A4CYP2C9CYP2C19KDM4ELMNA
SCHEMBL30150307 0.70 NR5A2 (0.38) CYP3A4CYP2C9CYP2C19KDM4ELMNA
SCHEMBL22916767 0.70 MMP1 (0.33) CYP3A4CYP2C9CYP2C19CTSLCTSB
SCHEMBL3163166 0.70 CTSL (0.54) CYP3A4CYP2C9CYP2C19KDM4ELMNA
SCHEMBL22916677 0.69 MAPT (0.41) CYP3A4CYP2C9CYP2C19LMNACYP1A2
SCHEMBL31711571 0.69 KDM4E (0.38) CYP3A4CYP2C9CYP2C19KDM4ELMNA
SCHEMBL31711565 0.69 CTSL (0.45) CYP3A4CYP2C9CYP2C19KDM4ELMNA
SCHEMBL5669058 0.69 TDP1 (0.41) CYP3A4CYP2C9CYP2C19KDM4ELMNA
SCHEMBL5669154 0.67 RARB (0.45) CYP3A4CYP2C9CYP2C19KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210022338-A1 ALKYNE COMPOUND AND ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210022338-A1 ALKYNE COMPOUND AND ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME C5, C9, C3AR1 CYP3A4 619/4885CYP2C9 288/4885CYP2C19 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.