SCHEMBL30150307

SCHEMBL30150307

CCCCC#Cc1cc(C(C)(C)C)cc(C#CCCCC)c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A2 O00482 1/20 0.38
NR5A1 Q13285 1/20 0.38
PGK1 P00558 2/20 0.37
GPR84 Q9NQS5 1/20 0.36
CYP2C19 P33261 4/20 0.35
CYP3A4 P08684 3/20 0.35
CYP1A2 P05177 3/20 0.35
CYP2C9 P11712 3/20 0.35
CYP2D6 P10635 2/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
APEX1 P27695 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
TSHR P16473 2/20 0.33
CTSL P07711 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15287905 0.75 PGK1 (0.38) PGK1GPR84CYP2C19CYP3A4CYP1A2
SCHEMBL7702123 0.73 CA2 (0.42) NR5A2NR5A1GPR84CYP2C19CYP3A4
SCHEMBL22916772 0.70 CYP3A4 (0.37) CYP2C19CYP3A4CYP1A2CYP2C9CYP2D6
SCHEMBL5667707 0.69 TDP1 (0.41) CYP2C19CYP3A4CYP1A2CYP2C9CYP2D6
SCHEMBL6117105 0.68 PGK1 (0.32) PGK1CYP2C19CYP3A4CYP1A2CYP2C9
SCHEMBL29089504 0.67 PGK1 (0.42) PGK1GPR84CYP2C19CYP3A4CYP1A2
SCHEMBL28564819 0.67 CYP3A4 (0.50) PGK1GPR84CYP2C19CYP3A4CYP1A2
SCHEMBL2814494 0.67 CYP3A4 (0.44) PGK1GPR84CYP2C19CYP3A4CYP1A2
SCHEMBL199679 0.66 CYP2C19 (0.53) NR5A2NR5A1CYP2C19CYP3A4CYP1A2
SCHEMBL27794423 0.66 PGK1 (0.48) PGK1GPR84CYP2C19CYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112745365-B Metallocene-containing phenol metal complex and preparation method and application thereof 中国石油化工股份有限公司 2023-10-10 CN disclosed
CN-112745405-B Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2023-03-14 CN disclosed
CN-112745444-B Olefin polymerization reaction and olefin polymer 中国石油化工股份有限公司 2023-02-28 CN disclosed