SCHEMBL229173

SCHEMBL229173

Cc1ccc2cc(Cl)ccc2n1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.63
POLB P06746 2/20 0.59
KDM4E B2RXH2 2/20 0.59
LMNA P02545 1/20 0.59
CASP6 P55212 1/20 0.59
HTR3A P46098 2/20 0.49
HRH4 Q9H3N8 1/20 0.49
NR4A2 P43354 1/20 0.47
ALDH1A1 P00352 2/20 0.46
BACE1 P56817 1/20 0.43
CYP2A6 P11509 1/20 0.43
KDM1A O60341 1/20 0.42
MEN1 O00255 1/20 0.42
USP2 O75604 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
HSD17B10 Q99714 1/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HRH3 Q9Y5N1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL383207 0.94 CYP1A2 (0.57) CYP1A2POLBKDM4ELMNACASP6
SCHEMBL1459737 0.84 CYP1A2 (0.61) CYP1A2POLBKDM4ELMNACASP6
SCHEMBL29447040 0.77 BACE1 (0.50) HTR3AHRH4NR4A2ALDH1A1BACE1
SCHEMBL198060 0.77 BACE1 (0.50) HTR3AHRH4NR4A2ALDH1A1BACE1
SCHEMBL29444268 0.77 CYP1A2 (1.00) CYP1A2POLBKDM4ELMNACASP6
SCHEMBL161703 0.77 CYP1A2 (1.00) CYP1A2POLBKDM4ELMNACASP6
SCHEMBL10259445 0.76 CYP1A2 (0.68) CYP1A2POLBKDM4ELMNACASP6
Iodide SCHEMBL31142554 0.76 CYP1A2 (0.95) CYP1A2POLBKDM4ELMNACASP6
SCHEMBL21632300 0.76 CYP1A2 (0.65) CYP1A2POLBKDM4ELMNACASP6
SCHEMBL2717077 0.76 CYP1A2 (0.56) CYP1A2POLBKDM4ELMNACASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979619-A Method for catalyzing dehydrogenation coupling reaction of nitrogen heteroaromatic ring compound and cyclic ether by using Bronsted acid 青岛职业技术学院 2021-06-18 CN claimed
CN-104447539-B A kind of two grades, the synthetic method of three-level aromatic amides 湖南大学 2017-09-15 CN claimed
CN-106565600-A Deuterated aza aromatic compound and synthesis method thereof 湖南大学 2017-04-19 CN claimed
US-4154780-A Preparation of dithiophosphoric acid diester-halides BAYER AKTIENGESELLSCHAFT (DE) 1979-05-15 US claimed
US-20250082633-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC (US) 2025-03-13 US disclosed
CN-116283759-B Preparation method of 2-monofluoromethylquinoline and derivatives thereof 济南大学 2025-02-28 CN disclosed
CN-118804912-A Compounds and methods for modulating splicing 雷密克斯医疗公司 2024-10-18 CN disclosed
EP-4436961-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING Remix Therapeutics Inc. (US) 2024-10-02 EP disclosed
WO-2024108774-A1 METAL-CATALYZED DOUBLE HYDROBORATION OF NITROGEN HETEROCYCLICS GUANGDONG TECHNION-ISRAEL INSTITUTE OF TECHNOLOGY (CN) 2024-05-30 WO disclosed
US-20240158412-A1 UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF FAXIAN THERAPEUTICS, LLC 2024-05-16 US disclosed
EP-4288442-A1 UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF Faxian Therapeutics, LLC (US) 2023-12-13 EP disclosed
CN-113862710-B Electrochemical synthesis method of dihydro-dipyrazole [3,4-b:4',3' -e ] pyridine compound 阜阳师范大学 2023-11-03 CN disclosed
EP-0038984-B1 PROCESS FOR THE PREPARATION OF CARBONIC-ACID ESTERS BAYER AG (DE) 1985-07-03 EP disclosed
EP-0138176-A2 Process for the preparation of quinolines BASF Aktiengesellschaft (DE) 1985-04-24 EP disclosed
EP-0132714-A2 Process for the preparation of quinolines BASF Aktiengesellschaft (DE) 1985-02-13 EP disclosed
US-4416884-A ANTIBIOTIC, BACTERICIDE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1983-11-22 US disclosed
US-4370275-A CATALYST OF COPPER, OXYGEN, HALOGEN, AND NITROGEN BASE BAYER AKTIENGESELLSCHAFT (DE) 1983-01-25 US disclosed
EP-0038984-A2 Process for the preparation of carbonic-acid esters BAYER AG (DE) 1981-11-04 EP disclosed
US-4154780-A Preparation of dithiophosphoric acid diester-halides BAYER AKTIENGESELLSCHAFT (DE) 1979-05-15 US disclosed
US-4154780-A Preparation of dithiophosphoric acid diester-halides BAYER AKTIENGESELLSCHAFT (DE) 1979-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250082633-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING RBM17, SNRPA, SNRPA1 CYP1A2 4609/4885POLB 289/4885KDM4E 3046/4885
US-20240158412-A1 UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF USP7, USP28, USP1 CYP1A2 3471/4885POLB 2982/4885KDM4E 545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.