Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.50 |
| ▸ | HTR3A | P46098 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | TEC | P42680 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447040 | 1.00 | BACE1 (0.50) | BACE1HTR3AHRH4CYP2A6HRH3 | |
| SCHEMBL3666214 | 0.90 | BACE1 (0.43) | BACE1HTR3AHRH4CYP2A6HRH3 | |
| SCHEMBL30506415 | 0.83 | NR4A2 (0.54) | BACE1HTR3ACYP2A6HRH3NR4A2 | |
| SCHEMBL2133059 | 0.83 | NR4A2 (0.54) | BACE1HTR3ACYP2A6HRH3NR4A2 | |
| SCHEMBL2130719 | 0.82 | BACE1 (0.72) | BACE1PIK3CGTECPLAU | |
| SCHEMBL3669666 | 0.81 | BACE1 (0.37) | BACE1HTR3AHRH4CYP2A6HRH3 | |
| SCHEMBL11109364 | 0.77 | HTR3A (0.45) | BACE1HTR3AHRH4CYP2A6HRH3 | |
| SCHEMBL934918 | 0.77 | HTR3A (0.45) | BACE1HTR3AHRH4CYP2A6HRH3 | |
| SCHEMBL22791436 | 0.77 | HTR3A (0.45) | BACE1HTR3AHRH4CYP2A6HRH3 | |
| SCHEMBL16289587 | 0.77 | HTR3A (0.45) | BACE1HTR3AHRH4CYP2A6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107163251-B | High temperature resistant poly arylidene thio-ester analog copolymer and preparation method thereof | 四川大学 | 2019-08-09 | — | — | CN | claimed |
| EP-2262789-A1 | 2-AMINOQUINOLINES | F. Hoffmann-La Roche AG (CH) | 2010-12-22 | — | — | EP | claimed |
| WO-2009109477-A1 | 2-AMINOQUINOLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-09-11 | — | — | WO | claimed |
| EP-1476448-A2 | AZABICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN COMPANY (US) | 2004-11-17 | — | — | EP | claimed |
| WO-2003070731-A2 | AZABICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN COMPANY (US) | 2003-08-28 | — | — | WO | claimed |
| US-20260083723-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS | TORAY INDUSTRIES, INC. (JP) | 2026-03-26 | — | — | US | disclosed |
| US-12570639-B2 | Tetrahydroquinoline derivative and medicinal use thereof | TORAY INDUSTRIES, INC. (JP) | 2026-03-10 | — | — | US | disclosed |
| EP-3429998-B3 | PROCESS FOR PREPARING QUINOLIN-2-YL-PHENYLAMINE DERIVATIVES AND THEIR SALTS | ABIVAX (FR) | 2026-02-11 | — | — | EP | disclosed |
| EP-4363415-B1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | TECNIMEDE SOCIEDADE TECNICO MEDICINAL SA (PT) | 2025-12-10 | — | — | EP | disclosed |
| US-12435061-B2 | Compounds and compositions for use in treating skin disorders | KAMARI PHARMA LTD. (IL) | 2025-10-07 | — | — | US | disclosed |
| EP-4583874-A1 | MULTITARGET NUCLEAR RECEPTOR LIGANDS BASED ON 2-(4-(QUINOLIN-2-YLOXY)PHENOXY)PROPANOIC ACID AND 2-(4-(QUINOXALIN-2-YLOXY)PHENOXY)PROPANOIC ACID FOR THE TREATMENT OF METABOLIC AND LIVER DISEASES | CHARLES UNIVERSITY, FACULTY OF PHARMACY IN HRADEC KRALOVE (CZ) | 2025-07-16 | — | — | EP | disclosed |
| EP-4574822-A2 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | Kamari Pharma Ltd. (IL) | 2025-06-25 | — | — | EP | disclosed |
| US-4444584-A | Ethyl 2[4-(7-chloroquinolin-3-yloxy)phenoxy]propionate, the N-oxide, and herbicidal compositions and methods employing them | ICI AUSTRALIA LIMITED (AU) | 1984-04-24 | — | — | US | disclosed |
| US-4440930-A | Herbicidally active quinoline or quinoxaline acetophenone oxime derivatives | PPG INDUSTRIES, INC. (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0098751-A2 | Quinolinyloxy(amino)phenols and alkoxyphenyloxy(amino)quinolines | ICI AUSTRALIA LIMITED (AU) | 1984-01-18 | — | — | EP | disclosed |
| EP-0029319-A2 | Quinolinyloxy(amino)phenoxyalkane carboxylic acid derivatives, process for their synthesis, herbicidal compositions containing them and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1981-05-27 | — | — | EP | disclosed |
| EP-0023785-A2 | Quinoxalinyloxyphenoxyalkane carboxylic acid derivatives, their preparation and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1981-02-11 | — | — | EP | disclosed |
| US-4236912-A | Quinolinyloxyphenoxy and quinolyinylthiophenoxy alkanoic acids and derivatives thereof and methods of herbicidal use | THE DOW CHEMICAL COMPANY (US) | 1980-12-02 | — | — | US | disclosed |
| US-4135045-A | PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1979-01-16 | — | — | US | disclosed |
| US-4048415-A | TITANIUM-ALUMINUM COORDINATION CATALYSTS | MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) | 1977-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12435061-B2 | Compounds and compositions for use in treating skin disorders | RDX, HAX1, F12 | BACE1 3562/4885HTR3A 2704/4885HRH4 1101/4885 |
| US-20260083723-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS | AIFM2, GPX1, SOD1 | BACE1 739/4885HTR3A 2858/4885HRH4 1016/4885 |
| US-12570639-B2 | Tetrahydroquinoline derivative and medicinal use thereof | AIFM2, GPX1, GPX4 | BACE1 1013/4885HTR3A 2016/4885HRH4 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.