SCHEMBL22917620 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	TDP1	Q9NUW8	2/20	0.42

▸	LMNA	P02545	3/20	0.40

▸	NR1I2	O75469	1/20	0.40

▸	ALDH1A1	P00352	1/20	0.40

▸	CYP1A2	P05177	1/20	0.40

▸	HTT	P42858	1/20	0.40

▸	HSD17B10	Q99714	1/20	0.40

▸	L3MBTL1	Q9Y468	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5027815	0.80	LMNA (0.59)	TDP1LMNANR1I2ALDH1A1CYP1A2
SCHEMBL1286154	0.77	LMNA (0.40)	TDP1LMNANR1I2ALDH1A1CYP1A2
SCHEMBL6699963	0.77	TDP1 (0.56)	TDP1LMNANR1I2ALDH1A1CYP1A2
SCHEMBL5028006	0.75	LMNA (0.59)	TDP1LMNANR1I2ALDH1A1CYP1A2
SCHEMBL10620808	0.75	LMNA (0.69)	TDP1LMNANR1I2ALDH1A1CYP1A2
SCHEMBL521727	0.75	LMNA (0.69)	TDP1LMNANR1I2ALDH1A1CYP1A2
SCHEMBL5052085	0.75	LMNA (0.59)	TDP1LMNANR1I2ALDH1A1CYP1A2
SCHEMBL5133813	0.75	LMNA (0.69)	TDP1LMNANR1I2ALDH1A1CYP1A2
SCHEMBL756618	0.75	LMNA (0.59)	TDP1LMNANR1I2ALDH1A1CYP1A2
SCHEMBL5051917	0.75	LMNA (0.59)	TDP1LMNANR1I2ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021013815-A1	METHODS OF TREATING MULTIPLE SCLEROSIS	ACTELION PHARMACEUTICALS LTD (CH)	2021-01-28	—	—	WO	disclosed