Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.56 |
| ▸ | CASP2 | P42575 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23480269 | 0.95 | FAAH (0.49) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL31088254 | 0.86 | FAAH (0.64) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL7163016 | 0.84 | NAAA (0.61) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL22912622 | 0.84 | FAAH (0.50) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL23375897 | 0.83 | CA2 (0.58) | FAAHCASP2DNM1NAAACNR1 | |
| SCHEMBL27110298 | 0.81 | CASP2 (0.63) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL23472179 | 0.81 | FAAH (0.61) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL25229329 | 0.81 | CASP2 (0.59) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL12792260 | 0.80 | CASP2 (0.62) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL12791885 | 0.80 | CASP2 (0.62) | FAAHCASP2DNM1NAAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021014415-A2 | SMALL MOLECULE INHIBITORS OF ACETYL COENZYME A SYNTHETASE SHORT CHAIN 2 (ACSS2) | CURADEV PHARMA PVT. LTD. (IN) | 2021-01-28 | — | — | WO | disclosed |