SCHEMBL2291950

SCHEMBL2291950

CS(=O)(=O)Cc1ccc(Br)c(CBr)c1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.41
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
FFAR1 O14842 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
BRD4 O60885 1/20 0.31
GSTO1 P78417 1/20 0.30
PTGS1 P23219 2/20 0.30
PTGS2 P35354 2/20 0.30
RCE1 Q9Y256 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28785803 0.86 PTPN1 (0.39) PTPN1CA1CA2FFAR1FFAR4
SCHEMBL2292381 0.78 PTPN1 (0.33) PTPN1CA2
SCHEMBL2294117 0.78 ALDH1A1 (0.43) CA1CA2
SCHEMBL2516047 0.76 PTPN1 (0.42) PTPN1CA1CA2GSTO1
SCHEMBL27672757 0.76 TSHR (0.36)
SCHEMBL2936648 0.75 TRPA1 (0.40) CA2
SCHEMBL18517162 0.74 ALDH1A1 (0.40) PTPN1CA1CA2RCE1
SCHEMBL7450435 0.74 CA2 (0.50) PTPN1CA1CA2BRD4
SCHEMBL26956115 0.74 ALDH1A1 (0.49) PTPN1CA1CA2
SCHEMBL2292751 0.74 THRA (0.40) PTPN1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2149545-B1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2016-10-05 EP disclosed
US-7994367-B2 Method for producing benzaldehyde compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-09 US disclosed
US-20100210879-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-19 US disclosed
EP-2149545-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210879-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND NQO1, C9, TRPA1 PTPN1 4716/4885CA1 624/4885CA2 292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.