Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17191962 | 0.90 | MRGPRX4 (0.58) | MRGPRX4MEN1KMT2APTGER1 | |
| SCHEMBL2317454 | 0.90 | RXRA (0.61) | MRGPRX4RXRAMEN1KMT2AHPGD | |
| SCHEMBL21180266 | 0.90 | HPGD (0.65) | MRGPRX4MEN1KMT2AHPGDRAB9A | |
| SCHEMBL1766201 | 0.89 | RXRA (0.55) | MRGPRX4RXRAMEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL16143333 | 0.89 | RXRA (0.60) | MRGPRX4RXRAMEN1KMT2AHPGD | |
| SCHEMBL15673277 | 0.87 | RXRA (0.62) | MRGPRX4RXRAMEN1KMT2AHPGD | |
| SCHEMBL22555979 | 0.87 | HPGD (0.48) | MRGPRX4RXRAMEN1KMT2AHPGD | |
| SCHEMBL15969027 | 0.87 | MEN1 (0.63) | MRGPRX4MEN1KMT2AHPGDLMNA | |
| SCHEMBL29136466 | 0.85 | HPGD (0.66) | MRGPRX4RXRAMEN1KMT2AHPGD | |
| SCHEMBL30102546 | 0.85 | RXRA (0.62) | MRGPRX4RXRAMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10358453-B2 | Antiviral compounds | ALIOS BIOPHARMA, INC. (US) | 2019-07-23 | — | — | US | disclosed |
| CN-101351442-B | Amide compound and use thereof | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2011-12-14 | — | — | CN | disclosed |
| US-8003699-B2 | Amide compound and use thereof for controlling plant diseases | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-23 | — | — | US | disclosed |
| US-7902400-B2 | N-(1,1-diemthylpropyl)-4-(2-propynyloxy)-3-methoxybenzamide; N-(2,2-diemthylpropyl)-4-(2-propynyloxy)-3-methoxybenzamide; controlling plant diseases | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-03-08 | — | — | US | disclosed |
| US-7714168-B2 | N-(1,1-diemthylpropyl)-4-(2-propynyloxy)-3-methoxybenzamide; N-(2,2-diemthylpropyl)-4-(2-propynyloxy)-3-methoxybenzamide; controlling plant diseases | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-05-11 | — | — | US | disclosed |
| US-20100105647-A1 | AMIDE COMPOUND AND USE THEREOF FOR CONTROLLING PLANT DISEASES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2010-04-29 | — | — | US | disclosed |
| EP-2151432-A1 | AMIDE COMPOUND AND USE THEREOF FOR CONTROLLING PLANT DISEASES | Sumitomo Chemical Company, Limited (JP) | 2010-02-10 | — | — | EP | disclosed |
| EP-1940779-B1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO (JP) | 2009-07-22 | — | — | EP | disclosed |
| US-20090131531-A1 | Amide Compounds and their Use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-21 | — | — | US | disclosed |
| CN-101351442-A | Amide compound and use thereof | SUMITOMO CHEMICAL CO (JP) | 2009-01-21 | — | — | CN | disclosed |
| US-20080319080-A1 | Amide Compounds and Their Use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-12-25 | — | — | US | disclosed |
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| EP-1940779-A2 | AMIDE COMPOUNDS AND THEIR USE | Sumitomo Chemical Company, Limited (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049729-A2 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131531-A1 | Amide Compounds and their Use | NAT1, ACAT2, NAAA | MRGPRX4 3512/4885RXRA 1423/4885MEN1 3713/4885 |
| US-10358453-B2 | Antiviral compounds | MAVS, SARS1, ZC3HAV1 | MRGPRX4 1868/4885RXRA 2200/4885MEN1 4812/4885 |
| US-20100105647-A1 | AMIDE COMPOUND AND USE THEREOF FOR CONTROLLING PLANT DISEASES | CYC1, CBR3, CBR1 | MRGPRX4 1977/4885RXRA 790/4885MEN1 3175/4885 |
| US-20080319080-A1 | Amide Compounds and Their Use | NAT1, ACAT2, NAAA | MRGPRX4 3472/4885RXRA 1303/4885MEN1 3820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.