SCHEMBL22919985

SCHEMBL22919985

CPc1cc(-c2ccccc2)cc(C)c1I

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.36
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SLC22A2 O15244 1/20 0.33
SLC22A1 O15245 1/20 0.33
SLC22A3 O75751 1/20 0.33
SLC6A4 P31645 1/20 0.33
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
ESR2 Q92731 1/20 0.32
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
TNKS2 Q9H2K2 1/20 0.30
PSMB5 P28074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21041692 0.88 ALDH1A1 (0.39) KDM4EALDH1A1HTTSMN1; SMN2SLC22A2
SCHEMBL26256413 0.82 ALDH1A1 (0.45) BRD4KDM4EALDH1A1HTTSMN1; SMN2
SCHEMBL25951072 0.81 ALDH1A1 (0.39) BRD4KDM4EALDH1A1HTTSMN1; SMN2
SCHEMBL23473199 0.78 ALDH1A1 (0.41) BRD4KDM4EALDH1A1HTTSMN1; SMN2
SCHEMBL25951067 0.75 TNKS2 (0.40) BRD4KDM4EALDH1A1HTTNPC1
SCHEMBL20663110 0.72 MAOA (0.41) KDM4EALDH1A1HTTSMN1; SMN2SLC22A2
SCHEMBL23893239 0.71 RAPGEF4 (0.33)
SCHEMBL19431477 0.68 ALDH1A1 (0.50) BRD4KDM4EALDH1A1HTTSMN1; SMN2
SCHEMBL879028 0.67 ALDH1A1 (0.47) ALDH1A1
SCHEMBL455953 0.66 HSD17B1 (0.42) BRD4KDM4EALDH1A1HTTPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3770166-B1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2021-10-06 EP disclosed
EP-3770166-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2021-01-27 EP disclosed