Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.51 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21377331 | 0.81 | LNPEP (0.48) | LNPEPACMSDTDP1PSMB5HDAC1 | |
| SCHEMBL20400991 | 0.76 | PSMB5 (0.41) | LNPEPACMSDTDP1PSMB5HDAC1 | |
| SCHEMBL29447639 | 0.76 | PSMB5 (0.41) | LNPEPACMSDTDP1PSMB5HDAC1 | |
| SCHEMBL16188025 | 0.76 | PSMB5 (0.46) | LNPEPACMSDTDP1PSMB5KDR | |
| SCHEMBL15465713 | 0.76 | HDAC1 (0.43) | LNPEPACMSDTDP1PSMB5HDAC1 | |
| SCHEMBL27572022 | 0.76 | ACMSD (0.42) | LNPEPACMSDTDP1PSMB5HDAC1 | |
| SCHEMBL24572384 | 0.75 | ACMSD (0.56) | LNPEPACMSDTDP1PSMB5HDAC1 | |
| SCHEMBL26984327 | 0.73 | ACMSD (0.47) | LNPEPACMSDTDP1PSMB5HDAC1 | |
| SCHEMBL11862219 | 0.72 | ACMSD (0.47) | ACMSDTDP1PSMB5HDAC1HDAC2 | |
| SCHEMBL2173463 | 0.72 | KDR (0.51) | LNPEPACMSDTDP1PSMB5HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021016333-A1 | ARYL SULFONAMIDES AS SMALL MOLECULE STAT3 INHIBITORS | UNIVERSITY OF HAWAII (US) | 2021-01-28 | — | — | WO | disclosed |