Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22920105 | 0.81 | LNPEP (0.51) | LNPEPCSNK1DCSNK1EPSMB5ACMSD | |
| SCHEMBL16188025 | 0.75 | PSMB5 (0.46) | LNPEPPSMB5ACMSDTDP1NPC1 | |
| SCHEMBL15465713 | 0.72 | HDAC1 (0.43) | LNPEPPSMB5ACMSDTDP1HDAC1 | |
| SCHEMBL27572022 | 0.72 | ACMSD (0.42) | LNPEPPSMB5ACMSDTDP1HDAC1 | |
| SCHEMBL24092986 | 0.72 | NCF1 (0.44) | KCNH2HTR1AACMSDHDAC1HDAC2 | |
| SCHEMBL12247662 | 0.70 | DYRK1A (0.42) | LNPEPPSMB5ACMSDTDP1KDR | |
| SCHEMBL24572384 | 0.69 | ACMSD (0.56) | LNPEPPSMB5ACMSDTDP1HDAC1 | |
| SCHEMBL2173463 | 0.69 | KDR (0.51) | LNPEPMAPK14PSMB5ACMSDTDP1 | |
| SCHEMBL2379783 | 0.67 | ACMSD (0.41) | LNPEPKCNH2PSMB5ACMSDTDP1 | |
| SCHEMBL15464531 | 0.67 | HDAC1 (0.42) | LNPEPACMSDHDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3101015-B1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME | EA PHARMA CO LTD (JP) | 2019-09-18 | — | — | EP | disclosed |