SCHEMBL22923073

SCHEMBL22923073

CCC(Oc1ncccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)n(N)c2=O)c(F)cc1Cl)C(N)=O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 8/20 0.33
BCAT1 P54687 3/20 0.33
BCAT2 O15382 2/20 0.33
ROCK2 O75116 6/20 0.32
MAPK8 P45983 1/20 0.32
CYP3A4 P08684 2/20 0.32
UGCG Q16739 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22923081 0.87 BCAT1 (0.34) BCAT1BCAT2ROCK2MAPK8CYP3A4
SCHEMBL39853 0.86 DHODH (0.33) DHODHBCAT1BCAT2MAPK8CYP3A4
SCHEMBL7018763 0.84 BCAT1 (0.37) BCAT1BCAT2ROCK2MAPK8CYP3A4
SCHEMBL7018246 0.83 ROCK2 (0.36) ROCK2MAPK8CYP3A4UGCG
SCHEMBL7019602 0.82 CYP1A2 (0.34) BCAT1BCAT2ROCK2CYP3A4
SCHEMBL7018403 0.82 DRD1 (0.35) BCAT1BCAT2ROCK2
SCHEMBL7021008 0.81 BCAT1 (0.32) BCAT1BCAT2ROCK2
SCHEMBL30877113 0.80 PPOX (0.33) DHODHBCAT1BCAT2CYP3A4UGCG
SCHEMBL28736996 0.80 DHODH (0.32) DHODH
SCHEMBL3952115 0.80 PPOX (0.41) DHODHBCAT1BCAT2CYP3A4UGCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021013800-A1 SUBSTITUTED N-PHENYL-N-AMINOUARCILS AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2021-01-28 WO disclosed