SCHEMBL39853

SCHEMBL39853

CCC(Oc1ncccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 10/20 0.33
CYP3A4 P08684 3/20 0.33
UGCG Q16739 3/20 0.33
BCAT1 P54687 3/20 0.33
BCAT2 O15382 2/20 0.33
P2RX3 P56373 1/20 0.32
MAPK8 P45983 1/20 0.32
PLAU P00749 2/20 0.32
PLG P00747 1/20 0.32
PLAT P00750 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27008034 0.91 BCAT1 (0.33) DHODHCYP3A4UGCGBCAT1BCAT2
SCHEMBL27007963 0.91 DHODH (0.33) DHODHCYP3A4UGCGBCAT1BCAT2
SCHEMBL3242002 0.90 DHODH (0.35) DHODHCYP3A4UGCGBCAT1BCAT2
SCHEMBL27047483 0.89 BCAT1 (0.37) DHODHBCAT1BCAT2
SCHEMBL22912587 0.88 ALDH1A1 (0.35) BCAT1PLAUPLGPLAT
SCHEMBL3952115 0.87 PPOX (0.41) DHODHCYP3A4UGCGBCAT1BCAT2
SCHEMBL3245240 0.87 DHODH (0.32) DHODHCYP3A4UGCGBCAT1BCAT2
SCHEMBL30877113 0.87 PPOX (0.33) DHODHCYP3A4UGCGBCAT1BCAT2
SCHEMBL1959750 0.87 BCAT1 (0.34) DHODHCYP3A4UGCGBCAT1BCAT2
Benzene SCHEMBL21843346 0.87 BCAT1 (0.34) DHODHCYP3A4UGCGBCAT1BCAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025108865-A1 HERBICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2025-05-30 WO claimed
US-11311014-B2 Crystalline forms of ethyl[3-[2-chloro-4-fluoro-5-(1-methyl-6-trifluoromethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-3-yl)phenoxy]-2-pyridyloxy]acetate BASF SE (DE) 2022-04-26 US claimed
US-20210137112-A1 Crystalline forms of ethyl[3-[2-chloro-4-fluoro-5-(1-methyl-6-trifluoromethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-3-yl)phenoxy]-2-pyridyloxy]acetate BASF SE (DE) 2021-05-13 US claimed
US-20200359631-A1 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE OR ITS SALT AND AT LEAST ONE PROTOPORPHYRINOGEN-IX OXIDASE INHIBITOR BASF SE (DE) 2020-11-19 US claimed
WO-2018178039-A1 CRYSTALLINE FORMS OF ETHYL[3-[2-CHLORO-4-FLUORO-5-(1-METHYL-6-TRIFLUOROMETHYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-3-YL)PHENOXY]-2-PYRIDYLOXY]ACETATE BASF SE (DE) 2018-10-04 WO claimed
US-9220268-B2 Herbicidal benzoxazinones BASF SE (DE) 2015-12-29 US claimed
US-20150342193-A1 Herbicidal Composition BASF SE (DE) 2015-12-03 US claimed
US-20150250181-A1 Herbicidal Benzoxazinones BASF SE (DE) 2015-09-10 US claimed
US-20150119239-A1 AGROCHEMICAL COMPOSITIONS BASF SE (DE) 2015-04-30 US claimed
US-20120088661-A1 FUNGICIDAL MIXTURES BASF SE (DE) 2012-04-12 US claimed
US-20120088665-A1 FUNGICIDAL MIXTURES BASF SE (DE) 2012-04-12 US claimed
US-20120088662-A1 FUNGICIDAL MIXTURES BASF SE (DE) 2012-04-12 US claimed
WO-2011161131-A1 HERBICIDAL MIXTURES BASF SE (DE) 2011-12-29 WO claimed
WO-2011110583-A2 FUNGICIDAL MIXTURES COMPRISING TRIAZOLE DERIVATIVES BASF SE (DE) 2011-09-15 WO claimed
WO-2011018486-A2 HERBICIDALLY ACTIVE COMPOSITION COMPRISING BENZOXAZINONES BASF SE (DE) 2011-02-17 WO claimed
US-20100190794-A1 Herbicidally Active Composition BASF SE (DE) 2010-07-29 US claimed
US-12610950-B2 Method for weed control in lawn or turf DISCOVERY PURCHASER CORPORATION (US) 2026-04-28 US disclosed
US-12565489-B2 Heterocyclyl pyrimidines and triazines as novel fungicides BAYER AKTIENGESELLSCHAFT (DE) 2026-03-03 US disclosed
WO-2010009847-A1 HETEROCYCLICALLY SUBSTITUTED AMIDES, METHOD FOR THE PRODUCTION THEREOF, AND USE AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2010-01-28 WO disclosed
EP-2147919-A1 Heterocyclic substituted amides, method for their manufacture and their use as herbicides Bayer CropScience Aktiengesellschaft (DE) 2010-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088661-A1 FUNGICIDAL MIXTURES CYP51A1, CYP1A2, MSMO1 DHODH 165/4885CYP3A4 76/4885UGCG 1605/4885
US-20150342193-A1 Herbicidal Composition DDT, AS3MT, ACHE DHODH 153/4885CYP3A4 352/4885UGCG 2652/4885
US-12565489-B2 Heterocyclyl pyrimidines and triazines as novel fungicides CBR1, CBR3, NOX1 DHODH 260/4885CYP3A4 298/4885UGCG 1202/4885
US-20120088662-A1 FUNGICIDAL MIXTURES CYP51A1, CYP1A2, PFAS DHODH 115/4885CYP3A4 57/4885UGCG 1845/4885
US-20210137112-A1 Crystalline forms of ethyl[3-[2-chloro-4-fluoro-5-(1-methyl-6-trifluoromethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-3-yl)phenoxy]-2-pyridyloxy]acetate CYP4X1, CYP2F1, RCC1 DHODH 2503/4885CYP3A4 77/4885UGCG 4142/4885
US-20150250181-A1 Herbicidal Benzoxazinones CYP4X1, AOX1, PRDX5 DHODH 357/4885CYP3A4 65/4885UGCG 1781/4885
US-20120088665-A1 FUNGICIDAL MIXTURES AS3MT, DPM1, SQOR DHODH 825/4885CYP3A4 151/4885UGCG 1575/4885
US-12610950-B2 Method for weed control in lawn or turf GHDC, WASF2, CA3 DHODH 2257/4885CYP3A4 1221/4885UGCG 1466/4885
US-20100190794-A1 Herbicidally Active Composition ECI1, ACLY, SQOR DHODH 356/4885CYP3A4 682/4885UGCG 1841/4885
US-11311014-B2 Crystalline forms of ethyl[3-[2-chloro-4-fluoro-5-(1-methyl-6-trifluoromethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-3-yl)phenoxy]-2-pyridyloxy]acetate RCC1, CYP4X1, HAX1 DHODH 2631/4885CYP3A4 103/4885UGCG 3909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.