SCHEMBL22923397

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24248250	0.88	ALDH1A1 (0.49)	HDAC6ALDH1A1TSHRRAPGEF4
	SCHEMBL21312751	0.83	KMT2A (0.53)	KMT2AALDH1A1ALOX15TSHRALOX12
	SCHEMBL21468596	0.82	ALDH1A1 (0.43)	HDAC6ALDH1A1RAPGEF4HDAC1SRC
	SCHEMBL22923405	0.79	RAPGEF4 (0.45)	KMT2ATXNTDP1MEN1NPC1
	SCHEMBL395621	0.79	KMT2A (0.41)	KMT2AALDH1A1MEN1NPC1RAB9A
	SCHEMBL18458655	0.77	MAPK13 (0.55)	HDAC6KMT2AALDH1A1L3MBTL1HSD17B1
	SCHEMBL21669510	0.75	MEN1 (0.44)	KMT2ATXNALDH1A1ALOX15TSHR
	SCHEMBL22923289	0.74	MAPK10 (0.47)	KMT2AALDH1A1ALOX15TSHRALOX12
	SCHEMBL22848450	0.73	ALDH1A1 (0.57)	KMT2AALDH1A1MAPK1HSD17B10L3MBTL1
	SCHEMBL1921964	0.71	ALDH1A1 (0.64)	HDAC6ALDH1A1RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.