SCHEMBL21312751

SCHEMBL21312751

Fc1cccc(F)c1Nc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.53
HSD17B10 Q99714 3/20 0.52
MEN1 O00255 5/20 0.50
MAPT P10636 5/20 0.50
ALDH1A1 P00352 5/20 0.50
TDP1 Q9NUW8 5/20 0.50
TSHR P16473 3/20 0.50
ALOX12 P18054 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ALOX15 P16050 2/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
MAPK1 P28482 1/20 0.50
PTGS2 P35354 1/20 0.50
HTR2B P41595 1/20 0.50
AR P10275 1/20 0.50
CYP3A4 P08684 3/20 0.46
KDM1A O60341 1/20 0.45
KDM4E B2RXH2 3/20 0.44
RAB9A P51151 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4945534 0.85 MAPT (0.50) KMT2AHSD17B10MEN1MAPTALDH1A1
SCHEMBL24237839 0.85 CXCR2 (0.51) KMT2AHSD17B10MEN1MAPTALDH1A1
SCHEMBL22923397 0.83 HDAC6 (0.40) KMT2AHSD17B10MEN1ALDH1A1TDP1
SCHEMBL20702679 0.81 HSD17B10 (0.48) KMT2AHSD17B10MEN1MAPTALDH1A1
SCHEMBL395621 0.81 KMT2A (0.41) KMT2AMEN1ALDH1A1KDM4ERAB9A
SCHEMBL3636604 0.80 KMT2A (0.54) KMT2AMEN1MAPTALDH1A1TDP1
SCHEMBL4947111 0.78 CXCR2 (0.58) KMT2AMEN1MAPTALDH1A1TDP1
SCHEMBL4355262 0.77 HSD17B10 (0.55) KMT2AHSD17B10MEN1MAPTALDH1A1
SCHEMBL29240832 0.76 HSD17B10 (0.48) KMT2AHSD17B10MEN1MAPTALDH1A1
SCHEMBL1704615 0.75 MAPT (0.56) KMT2AHSD17B10MEN1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435267-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2025-10-07 US disclosed
CN-112601753-B Fluorine-substituted polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2024-08-16 CN disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
CN-114388703-A Organic electroluminescent device and polycyclic compound for organic electroluminescent device 三星显示有限公司 2022-04-22 CN disclosed
US-20220123214-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-21 US disclosed
US-20220123214-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-21 US disclosed
US-20220037591-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-02-03 US disclosed
CN-112601753-A Fluorine substituted polycyclic aromatic compound 学校法人关西学院 2021-04-02 CN disclosed
WO-2019198698-A1 FLUORINE-SUBSTITUTED POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2019-10-17 WO disclosed
WO-2019198698-A1 FLUORINE-SUBSTITUTED POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2019-10-17 WO disclosed
WO-2019163732-A1 COMPOUND AND COLORING RESIN COMPOSITION 住友化学株式会社 2019-08-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 KMT2A 2002/4885HSD17B10 2668/4885MEN1 549/4885
US-20220123214-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE PIEZO1, SLC25A21, SLCO4C1 KMT2A 2036/4885HSD17B10 2013/4885MEN1 1605/4885
US-12435267-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device PIEZO1, SLC25A21, SLCO4C1 KMT2A 2036/4885HSD17B10 2013/4885MEN1 1605/4885
US-20220037591-A1 Polycyclic aromatic compound F11, C1R, RNF31 KMT2A 2002/4885HSD17B10 2668/4885MEN1 549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.