SCHEMBL1921964

SCHEMBL1921964

Cc1cccc(C)c1Nc1ccc(-c2ccc(Nc3c(C)cccc3C)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.64
RAPGEF4 Q8WZA2 10/20 0.50
CXCR2 P25025 1/20 0.44
HDAC6 Q9UBN7 4/20 0.40
HTR1D P28221 1/20 0.40
HPGD P15428 1/20 0.39
POLB P06746 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22202518 0.94 ALDH1A1 (0.58) ALDH1A1RAPGEF4CXCR2HPGD
SCHEMBL4278475 0.93 ALDH1A1 (0.72) ALDH1A1RAPGEF4CXCR2HDAC6HTR1D
SCHEMBL5134264 0.86 RAPGEF4 (0.68) ALDH1A1RAPGEF4CXCR2HPGD
SCHEMBL24248250 0.84 ALDH1A1 (0.49) ALDH1A1RAPGEF4CXCR2HDAC6LMNA
SCHEMBL24318169 0.84 ALDH1A1 (0.62) ALDH1A1RAPGEF4CXCR2HPGDPOLB
SCHEMBL8014673 0.83 ALDH1A1 (0.61) ALDH1A1RAPGEF4CXCR2HPGD
SCHEMBL30966312 0.82 PTGS2 (0.51) ALDH1A1CXCR2POLB
SCHEMBL17549426 0.82 PTGS2 (0.51) ALDH1A1CXCR2POLB
SCHEMBL17344732 0.82 ALDH1A1 (0.60) ALDH1A1RAPGEF4CXCR2HPGDLMNA
SCHEMBL801391 0.79 RAPGEF4 (0.79) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed