Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22923596 | 0.89 | CASP2 (0.55) | CASP2NAAACNR1EPHX1MEN1 | |
| SCHEMBL22923593 | 0.85 | MEN1 (0.41) | CASP2CNR1EPHX1MEN1KMT2A | |
| SCHEMBL22923592 | 0.80 | CASP2 (0.35) | CASP2NAAAEPHX1MEN1ALDH1A1 | |
| SCHEMBL20380968 | 0.79 | ALDH1A1 (0.44) | CASP2CNR1ALDH1A1MAPTHPGD | |
| SCHEMBL25685931 | 0.79 | CASP2 (0.43) | CASP2NAAACNR1EPHX1MEN1 | |
| SCHEMBL25851494 | 0.79 | CCR2 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL14951758 | 0.78 | CASP2 (0.66) | CASP2NAAACNR1EPHX1ALDH1A1 | |
| SCHEMBL889206 | 0.76 | CASP2 (0.69) | CASP2NAAACNR1EPHX1ALDH1A1 | |
| SCHEMBL889286 | 0.76 | CASP2 (0.69) | CASP2NAAACNR1EPHX1ALDH1A1 | |
| SCHEMBL889167 | 0.76 | CASP2 (0.69) | CASP2NAAACNR1EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021013693-A1 | ANTIBODY DRUG CONJUGATES (ADCS) WITH NAMPT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-01-28 | — | — | WO | disclosed |