Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22923842 | 0.92 | LMNA (0.45) | DRD2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL22923843 | 0.80 | MEN1 (0.49) | LMNAKDM4EMEN1KMT2A | |
| SCHEMBL22923930 | 0.76 | MEN1 (0.45) | DRD2HTR6LMNAMEN1KMT2A | |
| SCHEMBL30367422 | 0.76 | LMNA (0.51) | LMNAKDM4EMEN1KMT2A | |
| SCHEMBL22924008 | 0.75 | ALDH1A1 (0.46) | LMNAMEN1KMT2A | |
| SCHEMBL22923879 | 0.73 | LMNA (0.49) | LMNAKDM4EMEN1KMT2A | |
| SCHEMBL22923858 | 0.73 | LMNA (0.49) | LMNAKDM4EMEN1KMT2A | |
| SCHEMBL22923883 | 0.71 | KDM4E (0.40) | DRD2LMNAKDM4E | |
| SCHEMBL9731087 | 0.71 | LMNA (0.69) | DRD2HTR1BHTR6HTR2ALMNA | |
| SCHEMBL22923863 | 0.70 | LMNA (0.52) | LMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012717-A1 | ANTITUMOR COMPOUND USED AS AXL INHIBITOR AND USE THEREOF | 南京华威医药科技集团有限公司 | 2021-01-28 | — | — | WO | disclosed |