Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566836 | 0.84 | EPHX1 (0.57) | EPHX1POLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL21605299 | 0.82 | ALDH1A1 (0.36) | EPHX1ALDH1A1 | |
| SCHEMBL7080075 | 0.81 | POLB (0.48) | EPHX1POLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7823787 | 0.77 | EPHX1 (0.52) | EPHX1POLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL14031260 | 0.77 | EPHX1 (0.52) | EPHX1POLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL24743664 | 0.75 | ALDH1A1 (0.37) | EPHX1ALDH1A1CRBNALOX15TSHR | |
| SCHEMBL14214964 | 0.74 | EPHX1 (0.49) | EPHX1POLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL19425988 | 0.73 | POLB (0.46) | EPHX1POLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL21648769 | 0.72 | EPHX1 (0.47) | EPHX1POLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL14864526 | 0.72 | EPHX1 (0.51) | EPHX1POLBALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11447452-B2 | Agonists of peroxisome proliferator-activated receptor alpha and methods of use | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2022-09-20 | — | — | US | disclosed |
| US-11337968-B2 | Phenylquinoline compositions for treatment of ocular disorders and conditions | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2022-05-24 | — | — | US | disclosed |
| US-20210024469-A1 | AGONISTS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024469-A1 | AGONISTS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA AND METHODS OF USE | PPARG, PPARA, PPARD | EPHX1 1064/4885POLB 447/4885ALDH1A1 845/4885 |
| US-11337968-B2 | Phenylquinoline compositions for treatment of ocular disorders and conditions | PPARG, PPARA, PPARD | EPHX1 953/4885POLB 516/4885ALDH1A1 1092/4885 |
| US-11447452-B2 | Agonists of peroxisome proliferator-activated receptor alpha and methods of use | PPARG, PPARA, PPARD | EPHX1 1064/4885POLB 447/4885ALDH1A1 845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.