Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15672268 | 0.88 | LMNA (0.67) | MAPTPOLBKDM4EKMT2APKM | |
| SCHEMBL14938583 | 0.83 | MAPT (0.56) | MAPTPOLBKMT2APKMLMNA | |
| SCHEMBL14938584 | 0.83 | MAPT (0.56) | MAPTPOLBKMT2APKMLMNA | |
| SCHEMBL20847077 | 0.82 | CTRC (0.70) | MAPTPOLBKDM4EKMT2ALMNA | |
| SCHEMBL15677690 | 0.82 | CTRC (0.70) | MAPTPOLBKDM4EKMT2ALMNA | |
| SCHEMBL10356216 | 0.81 | RAB9A (0.74) | MAPTKMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL21538104 | 0.80 | KMT2A (0.64) | MAPTPOLBKDM4EKMT2ALMNA | |
| SCHEMBL28638805 | 0.80 | MAPT (0.63) | MAPTPOLBKDM4EKMT2AALDH1A1 | |
| SCHEMBL16182568 | 0.79 | LMNA (0.56) | MAPTPOLBKDM4EKMT2APKM | |
| SCHEMBL22925021 | 0.79 | MAPT (0.57) | MAPTPOLBKDM4EKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012264-A1 | TRIAZOLE SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2021-01-28 | — | — | WO | disclosed |