Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 7/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230759 | 0.91 | THRB (0.57) | THRBTSHRTGM2HPGDALDH1A1 | |
| SCHEMBL3358609 | 0.83 | THRB (0.54) | THRBTSHRHPGDTHRAALDH1A1 | |
| SCHEMBL3356443 | 0.83 | THRB (0.54) | THRBTSHRHPGDTHRAALDH1A1 | |
| SCHEMBL229250 | 0.82 | THRB (0.54) | THRBTSHRTGM2HPGDTHRA | |
| SCHEMBL229372 | 0.82 | THRB (0.54) | THRBTSHRTGM2HPGDTHRA | |
| SCHEMBL1064321 | 0.80 | THRB (0.42) | THRBTGM2ALDH1A1CYP3A4KMT2A | |
| SCHEMBL1067386 | 0.79 | THRB (0.51) | THRBTSHRTGM2HPGDTHRA | |
| SCHEMBL106615 | 0.79 | TSHR (0.47) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL1781744 | 0.77 | THRB (0.49) | THRBTSHRTGM2HPGDTHRA | |
| SCHEMBL231329 | 0.77 | THRB (0.59) | THRBTSHRTGM2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004437-A1 | METHOD FOR PRODUCING (METH)ACRYLOSILANES | WACKER CHEMIE AG (DE) | 2012-01-05 | — | — | US | disclosed |