Sugi Predict

Sugi Predict / Compounds / SCHEMBL231329

SCHEMBL231329

SCHEMBL231329

C=CC(=O)OCCC[Si](Oc1ccccc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 2/20 0.59
▸ TSHR P16473 5/20 0.47
▸ ALDH1A1 P00352 3/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ HPGD P15428 1/20 0.44
▸ TP53 P04637 2/20 0.40
▸ HIF1A Q16665 2/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ TDP1 Q9NUW8 2/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ HCAR2 Q8TDS4 1/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ TGM2 P21980 2/20 0.35
▸ AKR1B10 O60218 2/20 0.35
▸ AKR1B1 P15121 2/20 0.35
▸ RECQL P46063 1/20 0.33
▸ LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3356443 0.92 THRB (0.54) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL3358609 0.92 THRB (0.54) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL8899017 0.88 THRB (0.59) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL8899006 0.86 THRB (0.56) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL230344 0.86 THRB (0.56) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL230731 0.86 THRB (0.56) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL1063223 0.83 THRB (0.54) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL2168203 0.83 THRB (0.54) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL230779 0.83 HCAR2 (0.39) THRBALDH1A1TDP1L3MBTL1HCAR2
SCHEMBL230759 0.81 THRB (0.57) THRBTSHRALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6992147-B1 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2006-01-31 — — US claimed
CN-119505102-A Active energy ray-curable composition, cured product, and laminate 荒川化学工业株式会社 2025-02-25 — — CN disclosed
CN-118725623-A Active energy ray-curable composition, active energy ray-curable composition set product, cured product, and laminate 荒川化学工业株式会社 2024-10-01 — — CN disclosed
CN-115707741-A Coating agent for cyclic olefin resin, cured product, and laminate 荒川化学工业株式会社 2023-02-21 — — CN disclosed
CN-113444373-B Composition for modifying asphalt, modified asphalt, method for producing same, and asphalt mixture 李威风 2023-01-24 — — CN disclosed
CN-115109208-A Active energy ray-curable resin composition, coating agent set, cured product, and laminate 荒川化学工业株式会社 2022-09-27 — — CN disclosed
CN-115109207-A Active energy ray-curable resin composition, coating agent set, cured product, and laminate 荒川化学工业株式会社 2022-09-27 — — CN disclosed
CN-113444373-A Composition for modifying asphalt, modified asphalt, method for producing same, and asphalt mixture 李威风 2021-09-28 — — CN disclosed
CN-109957361-B Water-based binder and secondary battery 宁德时代新能源科技股份有限公司 2021-02-09 — — CN disclosed
US-9593234-B2 Rubber composition having intramolecular double bond THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-03-14 — — US disclosed
EP-1950239-A1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2008-07-30 — — EP disclosed
WO-2008031895-A1 SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS N.P.T. S.R.L. (IT) 2008-03-20 — — WO disclosed
WO-2007063011-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2007-06-07 — — WO disclosed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 — — US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 — — US disclosed
EP-1469002-A1 Method for stabilizing unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2004-10-20 — — EP disclosed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 — — US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 — — US disclosed
EP-1249454-A1 Preparation of unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2002-10-16 — — EP disclosed
US-5700874-A CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE BRIDGESTONE CORPORATION (JP) 1997-12-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 THRB 4533/4885TSHR 4650/4885ALDH1A1 402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.