Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620936 | 1.00 | PDE2A (0.33) | PDE2AKDM4EGLAHTTKMT2A | |
| SCHEMBL22925977 | 0.80 | CA12 (0.43) | KDM4EKMT2ASMN1; SMN2TDP1CYP2C9 | |
| SCHEMBL22925741 | 0.73 | CYP1A1 (0.36) | KDM4ECYP2C9 | |
| SCHEMBL29620857 | 0.73 | CYP1A1 (0.36) | KDM4ECYP2C9 | |
| SCHEMBL22925543 | 0.72 | ROCK2 (0.40) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL29909305 | 0.69 | TRPV6 (0.42) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL1655533 | 0.69 | TRPV6 (0.42) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL29620855 | 0.69 | NPSR1 (0.47) | PDE2AKDM4EKMT2AL3MBTL1KDM1A | |
| SCHEMBL22925930 | 0.69 | NPSR1 (0.47) | PDE2AKDM4EKMT2AL3MBTL1KDM1A | |
| SCHEMBL23774878 | 0.67 | KDM4E (0.58) | KDM4EGLAHTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |