Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1655533 | 1.00 | TRPV6 (0.42) | TRPV6KDM4EGLAHTTKMT2A | |
| SCHEMBL25702645 | 0.90 | KDM4E (0.54) | TRPV6KDM4EGLAHTTKMT2A | |
| SCHEMBL31469673 | 0.86 | KDM4E (0.37) | TRPV6KDM4EGLAHTTKMT2A | |
| SCHEMBL28697696 | 0.86 | KDM4E (0.37) | TRPV6KDM4EGLAHTTKMT2A | |
| Hydrochloric Acid SCHEMBL28697863 | 0.84 | KDM4E (0.36) | TRPV6KDM4EGLAHTTKMT2A | |
| SCHEMBL24567826 | 0.83 | QDPR (0.47) | TRPV6CHRNB2CHRNA4 | |
| SCHEMBL31536280 | 0.83 | QDPR (0.47) | TRPV6CHRNB2CHRNA4 | |
| SCHEMBL30945274 | 0.81 | CHRNB2 (0.41) | CHRNB2CHRNA4 | |
| SCHEMBL25326519 | 0.81 | CHRNB2 (0.41) | CHRNB2CHRNA4 | |
| SCHEMBL23517959 | 0.81 | CHRNB2 (0.33) | TRPV6KDM4EGLAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |