Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925525 | 0.81 | SMN1; SMN2 (0.49) | MAPK14MAPTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL945487 | 0.78 | ALDH1A1 (0.47) | MAPK14MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL22925644 | 0.74 | MIF (0.39) | MAPK14ALDH1A1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL22925890 | 0.72 | ALDH1A1 (0.50) | MAPK14MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL8151927 | 0.69 | SMN1; SMN2 (0.54) | ALDH1A1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL3110227 | 0.69 | ALDH1A1 (0.43) | MAPK14MAPTALDH1A1TSHRSMN1; SMN2 | |
| Bromide SCHEMBL3107381 | 0.68 | ALDH1A1 (0.42) | MAPK14ALDH1A1TSHRSMN1; SMN2POLB | |
| Bromide SCHEMBL3107377 | 0.67 | ALDH1A1 (0.41) | MAPK14ALDH1A1TSHRSMN1; SMN2POLB | |
| SCHEMBL17460634 | 0.66 | LTB4R (0.39) | MEN1MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29617408 | 0.66 | TSHR (0.46) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| US-20220274970-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-09-01 | — | — | US | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220274970-A1 | INHIBITOR COMPOUNDS | SERPINB1, MMP1, SSB | MAPK14 2817/4885MEN1 1826/4885MAPT 2083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.