Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22927731 | 0.90 | MAPK1 (0.43) | ALDH1A1HTTNPSR1MAPK1TSHR | |
| SCHEMBL22927759 | 0.88 | KMT2A (0.43) | ALDH1A1HTTHDAC6MAOAMAOB | |
| SCHEMBL22927760 | 0.88 | KCNH2 (0.39) | HTTNPSR1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL22927803 | 0.88 | HDAC6 (0.38) | ALDH1A1HTTRAB9ANPSR1MAPK1 | |
| SCHEMBL22927765 | 0.87 | MEN1 (0.35) | ALDH1A1RAB9AMAOBSMN1; SMN2MEN1 | |
| SCHEMBL22927766 | 0.86 | COPS5 (0.36) | ALDH1A1HTTNPSR1TSHRALOX15 | |
| SCHEMBL29434810 | 0.81 | LMNA (0.43) | ALDH1A1HTTNPSR1MAPK1TSHR | |
| SCHEMBL22927753 | 0.80 | HDAC6 (0.38) | F10ALDH1A1RAB9ANPSR1MAPK1 | |
| SCHEMBL22927770 | 0.80 | NR3C1 (0.41) | ALDH1A1HTTNPSR1MAPK1TSHR | |
| SCHEMBL22927676 | 0.80 | MAOB (0.51) | ALDH1A1RAB9ANPSR1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021016317-A1 | MODULATORS OF TREX1 | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2021-01-28 | — | — | WO | disclosed |