Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.55 |
| ▸ | RRM1 | P23921 | 1/20 | 0.54 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16328504 | 0.94 | RRM1 (0.62) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL22596633 | 0.84 | DPP7 (0.42) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL31283221 | 0.83 | DPP7 (0.67) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL29238181 | 0.83 | DPP7 (0.67) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL3798623 | 0.83 | DPP7 (0.67) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL3795617 | 0.83 | DPP7 (0.67) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL3791159 | 0.83 | DPP7 (0.67) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL13656048 | 0.81 | SIRT6 (0.55) | GRIA1SIRT6SIRT1CHRNB2CHRNB4 | |
| SCHEMBL22929126 | 0.80 | TSHR (0.42) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL10020956 | 0.80 | TSHR (0.39) | DPP7RRM1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10905766-B2 | Therapeutic compositions and methods for treatment of muscle wasting diseases | OREGON STATE UNIVERSITY (US) | 2021-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10905766-B2 | Therapeutic compositions and methods for treatment of muscle wasting diseases | TNNC1, PYGM, MYLK2 | DPP7 1133/4885RRM1 236/4885GNAI3 1522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.