SCHEMBL2292913

SCHEMBL2292913

CCC(C)Oc1cc(O)c(-c2c(O)cc(OC(C)CC)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.37
XBP1 P17861 1/20 0.37
ATM Q13315 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
ALOX15 P16050 5/20 0.35
ALDH1A1 P00352 4/20 0.35
CYP1A2 P05177 2/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ATP2A2 P16615 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ATP2A3 Q93084 1/20 0.35
CYP2C9 P11712 4/20 0.34
LMNA P02545 2/20 0.34
HSD17B10 Q99714 2/20 0.34
NR1I2 O75469 1/20 0.34
MIF P14174 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2292870 0.83 CA1 (0.41) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL15065550 0.81 CA2 (0.44) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL2288807 0.76 CA1 (0.41) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL2292354 0.75 CA1 (0.38) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL2293680 0.73 ELANE (0.49) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL2295824 0.73 CA1 (0.67) GAACA1CA2ALOX15ALDH1A1
SCHEMBL29888641 0.73 CA1 (0.67) GAACA1CA2ALOX15ALDH1A1
SCHEMBL2289370 0.72 LTA4H (0.46) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL2286896 0.72 CA2 (0.44) GAAATMCA1CA2ALOX15
SCHEMBL11432548 0.70 ADRB2 (0.46) GAACA1CA2ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346887-B1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES DOW TECHNOLOGY INVESTMENTS LLC (US) 2013-12-25 EP disclosed
US-8546600-B2 Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite DOW TECHNOLOGY INVESTMENTS LLC 2013-10-01 US disclosed
US-20110196166-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE DOW TECHNOLOGY INVESTMENTS LLC 2011-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110196166-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE SOST, PLCB3, PPIP5K2 GAA 4660/4885XBP1 3329/4885ATM 4181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.