SCHEMBL22930623

SCHEMBL22930623

c1ccc2c(c1)-c1ccccc1C21c2ccccc2C2(c3ccccc3-c3c2ccc2c3oc3ccccc32)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.41
ALOX5 P09917 3/20 0.39
AHR P35869 3/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP2C19 P33261 1/20 0.33
CDC25A P30304 1/20 0.33
CDC25B P30305 1/20 0.33
CDC25C P30307 1/20 0.33
NTRK1 P04629 1/20 0.33
PLK3 Q9H4B4 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
PRKDC P78527 5/20 0.32
PTGS2 P35354 1/20 0.32
DYRK1A Q13627 1/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CB P42338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16491702 0.98 PGR (0.42) PGRALOX5AHRMEN1KMT2A
SCHEMBL19886879 0.90 PGR (0.40) PGRALOX5AHRMEN1KMT2A
SCHEMBL21585303 0.89 PGR (0.43) PGRALOX5AHRMEN1KMT2A
SCHEMBL21113455 0.89 PGR (0.38) PGRALOX5AHRCYP2C19CDC25A
SCHEMBL18732153 0.89 AHR (0.44) PGRALOX5AHR
SCHEMBL18382952 0.88 PGR (0.39) PGRALOX5AHRMEN1KMT2A
SCHEMBL30818204 0.88 PGR (0.39) PGRALOX5AHRMEN1KMT2A
SCHEMBL16491813 0.88 ALOX5 (0.39) PGRALOX5AHRMEN1KMT2A
SCHEMBL18731708 0.88 AHR (0.47) PGRALOX5AHRKMT2ADYRK1A
SCHEMBL16491664 0.88 ALOX5 (0.36) PGRALOX5MEN1KMT2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same LG CHEM, LTD. 2021-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same NR2E3, ALDH1A2, CRY1 PGR 735/4885ALOX5 2498/4885AHR 668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.