Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 3/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22930696 | 0.88 | PRKDC (0.38) | PRKDCPARP14ALOX5IDO1TDO2 | |
| SCHEMBL22930627 | 0.86 | ALOX5 (0.38) | PRKDCPARP14ALOX5MAPTGPR3 | |
| SCHEMBL19299506 | 0.85 | PRKDC (0.36) | PRKDCPARP14ALOX5IDO1TDO2 | |
| SCHEMBL16250106 | 0.85 | GPR3 (0.39) | PRKDCPARP14ALOX5MAPTGPR3 | |
| SCHEMBL18731812 | 0.85 | ALOX5 (0.36) | PRKDCPARP14ALOX5MAPTPDK2 | |
| SCHEMBL22930694 | 0.82 | MAPT (0.39) | IDO1TDO2MAPTPLAUPDK2 | |
| SCHEMBL22930626 | 0.81 | PDK2 (0.36) | PRKDCPARP14ALOX5MAPTPDK2 | |
| SCHEMBL23184370 | 0.80 | PARP14 (0.39) | PRKDCPARP14ALOX5MAPTGPR3 | |
| SCHEMBL18731816 | 0.80 | ALOX5 (0.35) | PRKDCPARP14ALOX5PDK2GPR3 | |
| SCHEMBL21742531 | 0.80 | ALOX5 (0.49) | PRKDCPARP14ALOX5TDO2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10910567-B2 | Double spiro-type compound and organic light emitting diode comprising same | LG CHEM, LTD. | 2021-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10910567-B2 | Double spiro-type compound and organic light emitting diode comprising same | NR2E3, ALDH1A2, CRY1 | PRKDC 4693/4885PARP14 3074/4885ALOX5 2498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.