Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Tetrylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.78 |
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | GLA | P06280 | 1/20 | 0.78 |
| ▸ | HPGD | P15428 | 1/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.78 |
| ▸ | BLM | P54132 | 1/20 | 0.78 |
| ▸ | CA1 | P00915 | 10/20 | 0.52 |
| ▸ | CA2 | P00918 | 10/20 | 0.52 |
| ▸ | CA9 | Q16790 | 8/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrylammonium SCHEMBL6902448 | 1.00 | RECQL (0.78) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL10902456 | 0.91 | RECQL (0.70) | RECQLTSHRGLAHPGDMAPK1 | |
| Tetrapropylammonium SCHEMBL2289084 | 0.89 | RECQL (0.78) | RECQLTSHRGLAHPGDMAPK1 | |
| Tetramethylammonium Ion SCHEMBL1639322 | 0.88 | RECQL (0.84) | RECQLTSHRGLAHPGDMAPK1 | |
| Tetramethylammonium Ion SCHEMBL2290716 | 0.88 | RECQL (0.84) | RECQLTSHRGLAHPGDMAPK1 | |
| Tetramethylammonium Ion SCHEMBL589210 | 0.88 | RECQL (0.84) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL25262176 | 0.88 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22283888 | 0.88 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22283884 | 0.88 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL23387500 | 0.88 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870624-A | Cleaning method and composition | OTI GREENTECH GROUP AG | 2015-08-26 | — | — | CN | disclosed |
| CN-103841948-A | Method | PERACHEM LTD | 2014-06-04 | — | — | CN | disclosed |
| US-20110192789-A1 | METAL OR METAL OXIDE DEPOSITED FIBROUS MATERIALS | DREXEL UNIVERSITY (US) | 2011-08-11 | — | — | US | disclosed |
| WO-2010120730-A1 | HAZARDOUS SUBSTANCE REMOVING MATERIALS, APPARATUS AND METHODS | GLOBAL PROTECTION USA, INC. (US) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010028017-A2 | METAL OR METAL OXIDE DEPOSITED FIBROUS MATERIALS | DREXEL UNIVERSITY (US) | 2010-03-11 | — | — | WO | disclosed |