Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Demannose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demannose SCHEMBL6035884 | 1.00 | USP2 (0.47) | USP2SLCO1B1PDE4ALMNAL3MBTL1 | |
| Demannose SCHEMBL9818467 | 1.00 | USP2 (0.47) | USP2SLCO1B1PDE4ALMNAL3MBTL1 | |
| Demannose SCHEMBL27664482 | 1.00 | USP2 (0.47) | USP2SLCO1B1PDE4ALMNAL3MBTL1 | |
| Demannose SCHEMBL27656022 | 1.00 | USP2 (0.47) | USP2SLCO1B1PDE4ALMNAL3MBTL1 | |
| Demannose SCHEMBL22551090 | 1.00 | USP2 (0.47) | USP2SLCO1B1PDE4ALMNAL3MBTL1 | |
| Galactose SCHEMBL1904377 | 1.00 | USP2 (0.47) | USP2SLCO1B1PDE4ALMNAL3MBTL1 | |
| Demannose SCHEMBL27794573 | 0.98 | USP2 (0.46) | USP2SLCO1B1PDE4ALMNAL3MBTL1 | |
| Demannose SCHEMBL3393205 | 0.98 | USP2 (0.46) | USP2SLCO1B1PDE4ALMNAL3MBTL1 | |
| Demannose SCHEMBL9751218 | 0.96 | USP2 (0.44) | USP2SLCO1B1PDE4ALMNAL3MBTL1 | |
| Xylose SCHEMBL10181263 | 0.94 | USP2 (0.44) | USP2SLCO1B1PDE4ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104126743-B | Method for reducing furan generation in thermally processed food | 南昌大学 | 2016-06-29 | — | — | CN | claimed |
| CN-104126743-A | Method for reducing furan generation in thermally processed food | UNIV NANCHANG | 2014-11-05 | — | — | CN | claimed |
| CN-102321697-B | Method for producing mycophenolic acid by efficiently accumulating Penicillium brevicompactum and supplementing precursor in later period | UNIV EAST CHINA SCIENCE & TECH | 2013-07-24 | — | — | CN | claimed |
| CN-102127572-B | Method for producing mycophenolic acid from penicillium brevicompactum by high-efficiency accumulation | UNIV EAST CHINA SCIENCE & TECH | 2013-04-10 | — | — | CN | claimed |
| CN-102127572-A | Method for producing mycophenolic acid from penicillium brevicompactum by high-efficiency accumulation | UNIV EAST CHINA SCIENCE & TECH | 2011-07-20 | — | — | CN | claimed |
| US-20060257526-A1 | Method of producing malt alcohol beverages | SAPPORO BREWERIES LIMITED (JP) | 2006-11-16 | — | — | US | claimed |
| US-7135200-B2 | Process for producing malt alcoholic drink | SAPPORO BREWERIES LIMITED (JP) | 2006-11-14 | — | — | US | claimed |
| US-20230083622-A1 | ORAL NOURISHING COMPOSITION AND METHODS THEREOF | KALMARNA LIMITED (VG) | 2023-03-16 | — | — | US | disclosed |
| CN-112457916-B | Tobacco flavor and preparation method thereof | 湖北中烟工业有限责任公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-112940857-A | Tobacco flavor and preparation method and application thereof | 湖北中烟工业有限责任公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-112545046-A | Composition capable of reducing free radical content in cigarette smoke and preparation method thereof | 湖北中烟工业有限责任公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112457916-A | Tobacco flavor and preparation method thereof | 湖北中烟工业有限责任公司 | 2021-03-09 | — | — | CN | disclosed |
| CN-111905019-A | Traditional Chinese medicine formula for regulating intestinal tracts of cultured animals and preparation method thereof | 张世淇 | 2020-11-10 | — | — | CN | disclosed |
| US-20020142410-A1 | Malt beverage having stabilized flavor and methods of production thereof | CERVECERIA POLAR, C.A. | 2002-10-03 | — | — | US | disclosed |
| US-6372269-B1 | GRAIN MALT OR GRAIN MALT WORT AND GENETICALLY MODIFIED YEAST CELL PRODUCING ENHANCED AMOUNTS OF REDUCTASE ENZYME NATIVE TO YEAST CELLS AS COMPARED TO CELLS OF WILD-TYPE STRAIN OF SAID YEAST CELL WHICH PRODUCE REDUCTASE ENZYME | CERVECERIA POLAR, C.A. (VE) | 2002-04-16 | — | — | US | disclosed |
| US-20010031493-A1 | Simultaneous decolorization and detoxification of molasses spent wash using novel white rot-lignin-modifying fungus flavaodon flavus | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2001-10-18 | — | — | US | disclosed |
| WO-2000018249-A1 | PROCESS FOR CONTROLLING MAILLARD-TYPE GLYCATION OF WHEY PROTEINS AND PRODUCTS WITH ENHANCED FUNCTIONAL PROPERTIES | NEW ZEALAND DAIRY RESEARCH INSTITUTE (NZ) | 2000-04-06 | — | — | WO | disclosed |
| EP-0924294-A2 | Malt beverage having stabilized flavor and methods of production thereof | Rangel-Aldao, Rafael (VE) | 1999-06-23 | — | — | EP | disclosed |
| US-5821092-A | Production of 1,3-propanediol from glycerol by recombinant bacteria expressing recombinant diol dehydratase | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-10-13 | — | — | US | disclosed |
| EP-0773285-A2 | Malt beverage having stabilized flavor and methods of production thereof | Bravo, Adriana (VE) | 1997-05-14 | — | — | EP | disclosed |