SCHEMBL229364

SCHEMBL229364

O=C(O)COCC(=O)NCCOCCOCCOCCO

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
GLP1R P43220 8/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TSHR P16473 2/20 0.36
MAPK1 P28482 1/20 0.36
POLB P06746 1/20 0.35
RECQL P46063 1/20 0.33
NCF1 P14598 1/20 0.33
LMNA P02545 1/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA4 P22748 2/20 0.33
CA9 Q16790 2/20 0.33
CA14 Q9ULX7 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2743011 0.98 GLP1R (0.37) MEN1KMT2AGLP1RSMN1; SMN2TSHR
SCHEMBL2743010 0.93 SMN1; SMN2 (0.43) MEN1KMT2AGLP1RSMN1; SMN2TSHR
SCHEMBL13689237 0.89 GLP1R (0.39) MEN1KMT2AGLP1RSMN1; SMN2TSHR
SCHEMBL7950916 0.89 MEN1 (0.42) MEN1KMT2ASMN1; SMN2TSHRMAPK1
SCHEMBL27409309 0.88 TSHR (0.44) GLP1RSMN1; SMN2TSHRMAPK1RECQL
SCHEMBL24855312 0.84 GLP1R (0.43) MEN1KMT2AGLP1RSMN1; SMN2TSHR
SCHEMBL13062338 0.84 MEN1 (0.38) MEN1KMT2AGLP1RSMN1; SMN2TSHR
SCHEMBL422917 0.84 GLP1R (0.38) MEN1KMT2AGLP1RSMN1; SMN2TSHR
SCHEMBL13274091 0.84 GLP1R (0.41) MEN1KMT2AGLP1RSMN1; SMN2TSHR
SCHEMBL18723358 0.84 GLP1R (0.46) MEN1KMT2AGLP1RSMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8415510-B2 Synthesis of a PEG-6 moiety from commercial low-cost chemicals GE HEALTHCARE LIMITED (GB) 2013-04-09 US claimed
EP-2268609-B1 Synthesis of a PEG-6 moiety from commercial low-cost chemicals GE HEALTHCARE LTD (GB) 2013-01-30 EP claimed
EP-2268609-A1 SYNTHESIS OF A PEG-6 MOIETY FROM COMMERCIAL LOW-COST CHEMICALS GE Healthcare Limited (GB) 2011-01-05 EP claimed
US-20100324264-A1 SYNTHESIS OF A PEG-6 MOIETY FROM COMMERCIAL LOW-COST CHEMICALS GE HEALTHCARE LIMITED (GB) 2010-12-23 US claimed
WO-2009108484-A1 SYNTHESIS OF A PEG-6 MOIETY FROM COMMERCIAL LOW-COST CHEMICALS GE HEALTHCARE LIMITED (GB) 2009-09-03 WO claimed
US-8536375-B2 Synthesis of obtaining modified polyethylene glycol intermediates GE HEALTHCARE LIMITED (GB) 2013-09-17 US disclosed
US-8536375-B2 Synthesis of obtaining modified polyethylene glycol intermediates GE HEALTHCARE LIMITED (GB) 2013-09-17 US disclosed
US-8536375-B2 Synthesis of obtaining modified polyethylene glycol intermediates GE HEALTHCARE LIMITED (GB) 2013-09-17 US disclosed
US-8415510-B2 Synthesis of a PEG-6 moiety from commercial low-cost chemicals GE HEALTHCARE LIMITED (GB) 2013-04-09 US disclosed
US-8415510-B2 Synthesis of a PEG-6 moiety from commercial low-cost chemicals GE HEALTHCARE LIMITED (GB) 2013-04-09 US disclosed
US-8415510-B2 Synthesis of a PEG-6 moiety from commercial low-cost chemicals GE HEALTHCARE LIMITED (GB) 2013-04-09 US disclosed
EP-2268609-B1 Synthesis of a PEG-6 moiety from commercial low-cost chemicals GE HEALTHCARE LTD (GB) 2013-01-30 EP disclosed
US-20120004423-A1 SYNTHESIS OF OBTAINING MODIFIED POLYETHYLENE GLYCOL INTERMEDIATES GE HEALTHCARE LIMITED (GB) 2012-01-05 US disclosed
EP-2370501-A1 SYNTHESIS OF OBTAINING MODIFIED POLYETHYLENE GLYCOL INTERMEDIATES GE Healthcare Limited (GB) 2011-10-05 EP disclosed
EP-2268609-A1 SYNTHESIS OF A PEG-6 MOIETY FROM COMMERCIAL LOW-COST CHEMICALS GE Healthcare Limited (GB) 2011-01-05 EP disclosed
US-20100324264-A1 SYNTHESIS OF A PEG-6 MOIETY FROM COMMERCIAL LOW-COST CHEMICALS GE HEALTHCARE LIMITED (GB) 2010-12-23 US disclosed
US-20100324264-A1 SYNTHESIS OF A PEG-6 MOIETY FROM COMMERCIAL LOW-COST CHEMICALS GE HEALTHCARE LIMITED (GB) 2010-12-23 US disclosed
US-20100324264-A1 SYNTHESIS OF A PEG-6 MOIETY FROM COMMERCIAL LOW-COST CHEMICALS GE HEALTHCARE LIMITED (GB) 2010-12-23 US disclosed
WO-2010074935-A1 SYNTHESIS OF OBTAINING MODIFIED POLYETHYLENE GLYCOL INTERMEDIATES GE HEALTHCARE LIMITED (GB) 2010-07-01 WO disclosed
WO-2009108484-A1 SYNTHESIS OF A PEG-6 MOIETY FROM COMMERCIAL LOW-COST CHEMICALS GE HEALTHCARE LIMITED (GB) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004423-A1 SYNTHESIS OF OBTAINING MODIFIED POLYETHYLENE GLYCOL INTERMEDIATES COASY, DHPS, FASN MEN1 2396/4885KMT2A 2028/4885GLP1R 3094/4885
US-20100324264-A1 SYNTHESIS OF A PEG-6 MOIETY FROM COMMERCIAL LOW-COST CHEMICALS GAS6, LNPEP, BMP6 MEN1 2158/4885KMT2A 1884/4885GLP1R 497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.