Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2293804 | 1.00 | NPC1 (0.50) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL3782388 | 0.88 | MAPT (0.40) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL3782384 | 0.88 | MAPT (0.40) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL5050582 | 0.83 | MAPT (0.48) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL29966795 | 0.83 | MAPT (0.48) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL28557804 | 0.83 | MAPT (0.48) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL5050581 | 0.83 | MAPT (0.48) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL3770487 | 0.82 | TRPA1 (0.38) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL3656662 | 0.82 | TRPA1 (0.38) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL3776016 | 0.81 | TRPA1 (0.39) | NPC1MAPTRAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398370-B1 | LONG-LASTING MOP | ECOLAB INC (US) | 2013-12-04 | — | — | EP | claimed |
| EP-1967171-B1 | Production method of an adhesive patch | TEIKOKU SEIYAKU KK (JP) | 2012-06-13 | — | — | EP | claimed |
| EP-1059370-B1 | Reduced shrinkage in metallocene isotactic polypropylene fibers | TOTAL PETROCHEMICALS RES FELUY (BE) | 2010-09-01 | — | — | EP | claimed |
| EP-1873292-B1 | Multicomposite variable-density multilayer non-woven fabric and method for manufacturing it | MARANGHI MARCO (IT) | 2009-11-11 | — | — | EP | claimed |
| EP-1304218-B1 | PLASTIC FILM FOR MEDICAL LIQUID CONTAINER | FUJIMORI KOGYO CO LTD (JP) | 2009-08-05 | — | — | EP | claimed |
| US-7994340-B2 | Azolylmethyloxiranes, their use for controlling phytopathogenic fungi, and compositions comprising them | BASF SE (DE) | 2011-08-09 | — | — | US | disclosed |
| US-20100311581-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | BASF SE (DE) | 2010-12-09 | — | — | US | disclosed |
| EP-2224812-A2 | AZOLYLMETHYLOXIRANES, USE THEREOF AND AGENTS CONTAINING THE SAME | BASF SE (DE) | 2010-09-08 | — | — | EP | disclosed |
| US-20100087321-A1 | Azolylmethyloxiranes, their use for Controlling Phytopathogenic Fungi, and Compositions Comprising Them | BASF SE (DE) | 2010-04-08 | — | — | US | disclosed |
| EP-2096921-A1 | AZOLYLMETHYLOXIRANES, THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI, AND COMPOSITIONS COMPRISING THEM | BASF SE (DE) | 2009-09-09 | — | — | EP | disclosed |
| WO-2009077471-A2 | AZOLYLMETHYLOXIRANES, USE THEREOF AND AGENTS CONTAINING THE SAME | BASF SE (DE) | 2009-06-25 | — | — | WO | disclosed |
| WO-2008077724-A1 | AZOLYLMETHYLOXIRANES, THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI, AND COMPOSITIONS COMPRISING THEM | BASF SE (DE) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087321-A1 | Azolylmethyloxiranes, their use for Controlling Phytopathogenic Fungi, and Compositions Comprising Them | PAH, AKR1C4, NAT1 | NPC1 2386/4885MAPT 4110/4885RAB9A 4527/4885 |
| US-20100311581-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | XDH, DAO, DHODH | NPC1 4699/4885MAPT 3819/4885RAB9A 4197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.