Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3661458 | 1.00 | TRPA1 (0.39) | TRPA1ALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL3775608 | 0.88 | NFE2L2 (0.38) | TRPA1NPC1SMN1; SMN2KMT2APKM | |
| SCHEMBL3662224 | 0.88 | NFE2L2 (0.38) | TRPA1NPC1SMN1; SMN2KMT2APKM | |
| SCHEMBL3770487 | 0.87 | TRPA1 (0.38) | TRPA1ALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL3656662 | 0.87 | TRPA1 (0.38) | TRPA1ALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL3782388 | 0.86 | MAPT (0.40) | TRPA1ALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL3782384 | 0.86 | MAPT (0.40) | TRPA1ALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL3773765 | 0.84 | ALDH1A1 (0.33) | TRPA1ALDH1A1KMT2ACES2CES1 | |
| SCHEMBL3773771 | 0.84 | ALDH1A1 (0.33) | TRPA1ALDH1A1KMT2ACES2CES1 | |
| SCHEMBL5050582 | 0.81 | MAPT (0.48) | TRPA1ALDH1A1MAPTHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317515-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | BASF SE (DE) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317515-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | XDH, NOX5, TET1 | TRPA1 2075/4885ALDH1A1 20/4885MAPT 3389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.