Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1324347 | 0.88 | DDB1 (0.42) | DDB1CRBNSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL13651747 | 0.79 | DDB1 (0.39) | DDB1CRBNSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2297578 | 0.73 | DDB1 (0.49) | DDB1CRBNSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28436910 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAALDH1A1GAATSHR | |
| SCHEMBL12424729 | 0.69 | DDB1 (0.47) | DDB1CRBNSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL12355229 | 0.69 | DDB1 (0.47) | DDB1CRBNSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1086370 | 0.69 | ALDH1A1 (0.60) | DDB1CRBNALDH1A1GAANAAA | |
| SCHEMBL10611547 | 0.68 | DDB1 (0.62) | DDB1CRBNSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL11868898 | 0.68 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAALDH1A1GAACTSL | |
| SCHEMBL2361135 | 0.67 | DDB1 (0.77) | DDB1CRBNSMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190497-A1 | Process for production of 2,5 dioxopyrrolidine 3 carboxylate | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190497-A1 | Process for production of 2,5 dioxopyrrolidine 3 carboxylate | REN, PKD1, KCNT1 | DDB1 3570/4885CRBN 4418/4885SMN1; SMN2 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.