SCHEMBL2294

SCHEMBL2294

Cc1cn([C@@]2(F)C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TK1 P04183 6/20 0.43
LMNA P02545 3/20 0.40
ALB P02768 2/20 0.40
BLM P54132 2/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
ADRA1A P35348 1/20 0.40
TSHR P16473 2/20 0.40
PKM P14618 1/20 0.40
PMP22 Q01453 1/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29943756 1.00 TK1 (0.43) TK1LMNAALBBLMALDH1A1
Trichloroethylene SCHEMBL9395208 0.93 TK1 (0.41) TK1LMNAALBBLMTSHR
SCHEMBL28551951 0.87 LMNA (0.51) TK1LMNABLMADRA1ATSHR
SCHEMBL28846549 0.86 TK1 (0.35) TK1
SCHEMBL8846493 0.86 TK1 (0.50) TK1LMNABLMADRA1ATSHR
SCHEMBL29364921 0.85 TK1 (0.45) TK1LMNAALBBLMALDH1A1
SCHEMBL135210 0.84 TK1 (0.44) TK1LMNAALBBLMALDH1A1
SCHEMBL16187026 0.84 TK1 (0.44) TK1LMNAALBBLMALDH1A1
SCHEMBL4809531 0.84 TK1 (0.44) TK1LMNAALBBLMALDH1A1
SCHEMBL1490858 0.84 TK1 (0.42) TK1LMNAALBBLMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 977 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025226286-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS IMAGING OF MULTIPLE POSITRON EMISSION TOMOGRAPHY (PET) TRACERS MULTIF UNCTIONAL IMAGING LLC (US) 2025-10-30 WO claimed
US-20250329024-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS IMAGING OF MULTIPLE POSITRON EMISSION TOMOGRAPHY (PET) TRACERS MultiFunctional Imaging LLC (US) 2025-10-23 US claimed
EP-4344736-A2 METHODS FOR CALCULATING BOUNDED DOSE-VOLUME HISTOGRAMS (DVH) FOR EVALUATING A TREATMENT PLAN RefleXion Medical, Inc. (US) 2024-04-03 EP claimed
US-20230414704-A1 Compositions Containing a Pharmacophore with Selectivity to Diseased Tissue and Methods of Making Same SANFORD-BURNHAM MEDICAL DISCOVERY INSTITUTE 2023-12-28 US claimed
CN-116916936-A Compositions and methods for delivering RNA 再生技术有限责任公司 2023-10-20 CN claimed
EP-3218333-B1 FLUORIDE TRAPPING ARRANGEMENT GE HEALTHCARE LTD (GB) 2023-06-07 EP claimed
US-11648418-B2 Systems and methods for biological adaptive radiotherapy REFLEXION MEDICAL, INC. (US) 2023-05-16 US claimed
US-20230068052-A1 ELUENT SOLUTION GE HEALTHCARE LTD (GB) 2023-03-02 US claimed
CN-109154671-B Radioactivity detection 赫尔大学 2022-10-04 CN claimed
CN-109154671-A RADIOACTIVITY DETECTION 赫尔大学 2019-01-04 CN claimed
WO-1999058723-A1 HETERODUPLEX MUTATIONAL VECTORS AND USE THEREOF IN BACTERIA KIMERAGEN, INC. (US) 1999-11-18 WO claimed
CN-1214629-A Solid immediate release dosage form and process for preparing same BOEHRINGER MANNHEIM GMBH (DE) 1999-04-21 CN claimed
US-5869097-A OSMOTIC CAPLET EXIT FOR DELIVERING A PRESELECTED DOSE OF DRUG ALZA CORPORATION (US) 1999-02-09 US claimed
US-5846987-A Retroviral protease inhibiting compounds ABBOTT LABORATORIES (US) 1998-12-08 US claimed
CN-1154111-A New lipid esters of nucleoside monophosphates and their use as immunosuppressive drugs BOEHRINGER MANNHEIM GMBH (DE) 1997-07-09 CN claimed
US-5635523-A ADMINISTERING MIXTURE OF 5-(N-(N-((N-METHYL-N-((2-ISOPROPYL-4-THIAZOLYL)METHYL) -AMINO)CARBONYL)VALINYL)AMINO)-2-(N-((5-THIAZOLYL)METHOXYCARBONYL)AMINO)-1,6-DIPHENYL-3-HYDROXYHEXANE OR SALT AND REVERSE TRASCRIPTASE INHIBITOR ABBOTT LABORATORIES (US) 1997-06-03 US claimed
EP-0727419-A2 Retroviral protease inhibiting compounds Abbott Laboratories (US) 1996-08-21 EP claimed
CN-1032258-C Phospholipid derivatives of nucleosides, processes for prepn. thereof and use thereof as antiviral medicaments BOCHRINGER MANNHEIM GMBH (DE) 1996-07-10 CN claimed
US-5358721-A Antiviral therapy ALZA CORPORATION (US) 1994-10-25 US claimed
CN-1059149-A New nucleoside phospholipid derivant, they method for making and as the application of antiviral BOEHRINGER MANNHEIM GMBH (DE) 1992-03-04 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230068052-A1 ELUENT SOLUTION ABCB11, IPO5, PFAS TK1 397/4885LMNA 2407/4885ALB 4680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.