Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.44 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292379 | 0.92 | TSHR (0.50) | ALDH1A1GAAEPHX2LMNAKMT2A | |
| SCHEMBL2291074 | 0.92 | LMNA (0.53) | ALDH1A1RAB9AGAAEPHX2LMNA | |
| SCHEMBL2296034 | 0.89 | KMT2A (0.51) | ALDH1A1GAAEPHX2LMNAKMT2A | |
| SCHEMBL2289836 | 0.89 | EPHX2 (0.47) | ALDH1A1GAAEPHX2LMNAKMT2A | |
| SCHEMBL2294491 | 0.88 | EPHX2 (0.45) | ALDH1A1GAAEPHX2LMNAKMT2A | |
| SCHEMBL2292202 | 0.87 | MEN1 (0.50) | ALDH1A1EPHX2LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL2292819 | 0.86 | LMNA (0.55) | ALDH1A1GAAEPHX2LMNAKMT2A | |
| SCHEMBL2296051 | 0.85 | PKM (0.52) | ALDH1A1RAB9AGAAEPHX2LMNA | |
| SCHEMBL2295386 | 0.85 | KMT2A (0.51) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL2292594 | 0.83 | ALDH1A1 (0.52) | ALDH1A1GAALMNACYP2C9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190300-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2011-08-04 | — | — | US | disclosed |
| US-20110190300-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190300-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | CACNA1E, CACNA1B, CACNA1S | ALDH1A1 1349/4885RAB9A 2436/4885GAA 3413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.