SCHEMBL2295386

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2289836	0.90	EPHX2 (0.47)	KMT2AMEN1ALDH1A1LMNAKDM4E
	SCHEMBL2291074	0.89	LMNA (0.53)	KMT2AMEN1ALDH1A1LMNAHSD17B10
	SCHEMBL2292064	0.87	KMT2A (0.50)	KMT2AMEN1ALDH1A1LMNATSHR
	SCHEMBL2292202	0.86	MEN1 (0.50)	KMT2AMEN1ALDH1A1LMNATSHR
	SCHEMBL2292379	0.85	TSHR (0.50)	KMT2AMEN1ALDH1A1LMNATSHR
	SCHEMBL2294071	0.85	ALDH1A1 (0.51)	KMT2AMEN1ALDH1A1LMNAHSD17B10
	SCHEMBL2294488	0.83	L3MBTL1 (0.49)	ALDH1A1LMNATSHRKDM4EL3MBTL1
	SCHEMBL2296034	0.83	KMT2A (0.51)	KMT2AMEN1ALDH1A1LMNATSHR
	SCHEMBL2292731	0.83	TRPV1 (0.49)	KMT2AALDH1A1LMNAKDM4EL3MBTL1
	SCHEMBL2294491	0.82	EPHX2 (0.45)	KMT2AMEN1ALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.