Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.34 |
| ▸ | JAK1 | P23458 | 3/20 | 0.34 |
| ▸ | TYK2 | P29597 | 3/20 | 0.34 |
| ▸ | JAK3 | P52333 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 16/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22942013 | 0.89 | ALOX15 (0.34) | — | |
| SCHEMBL22941983 | 0.87 | SMYD3 (0.34) | — | |
| SCHEMBL22941569 | 0.87 | — | — | |
| SCHEMBL22941981 | 0.86 | LMNA (0.32) | — | |
| SCHEMBL22941985 | 0.86 | — | — | |
| SCHEMBL22941526 | 0.85 | KMT2A (0.31) | — | |
| SCHEMBL22941528 | 0.85 | KMT2A (0.31) | — | |
| SCHEMBL22941555 | 0.85 | DRD2 (0.30) | — | |
| SCHEMBL22941560 | 0.85 | — | — | |
| SCHEMBL22941558 | 0.83 | ALOX15 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018834-A1 | CYCLIC DIONES AS HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-02-04 | — | — | WO | disclosed |