SCHEMBL22941983

SCHEMBL22941983

CC#Cc1cc(C)c(C2C(=O)CC3(CCC(NC(=O)CN)CC3)CC2=O)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SMYD3 Q9H7B4 2/20 0.34
NSD2 O96028 1/20 0.31
SETD2 Q9BYW2 1/20 0.31
LMNA P02545 2/20 0.31
HPGD P15428 2/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2B Q13224 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22941559 0.90 NPSR1 (0.38) LMNAHPGDSMN1; SMN2
SCHEMBL22942013 0.89 ALOX15 (0.34)
SCHEMBL22941977 0.87 LMNA (0.30) LMNAHPGD
SCHEMBL22941976 0.87 LMNA (0.34) LMNAHPGDSMN1; SMN2
SCHEMBL22941978 0.87 JAK2 (0.34)
SCHEMBL22941981 0.86 LMNA (0.32) LMNA
SCHEMBL22941985 0.86
SCHEMBL22941528 0.85 KMT2A (0.31)
SCHEMBL22941555 0.85 DRD2 (0.30)
SCHEMBL22941526 0.85 KMT2A (0.31) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021018834-A1 CYCLIC DIONES AS HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2021-02-04 WO disclosed