Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | ALPG | P10696 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | GBA1 | P04062 | 1/20 | 0.59 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18162478 | 0.86 | MAPT (0.60) | RAB9AKMT2AMEN1KDM4EMAPT | |
| SCHEMBL229747 | 0.84 | RAB9A (0.59) | RAB9AKMT2AMEN1KDM4ENPC1 | |
| SCHEMBL3759875 | 0.84 | MAPT (1.00) | RAB9AKMT2AMEN1KDM4EMAPT | |
| Phosphoric Acid Monomethyl Ester SCHEMBL28508950 | 0.84 | RAB9A (0.52) | RAB9AKMT2AMEN1KDM4EMAPT | |
| SCHEMBL6831731 | 0.83 | MAPK10 (0.53) | RAB9AKMT2AMEN1KDM4EMAPT | |
| SCHEMBL4815674 | 0.82 | ASIC3 (0.54) | RAB9AKMT2AMEN1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL4808551 | 0.81 | ASIC3 (0.52) | RAB9AKMT2AMEN1KDM4EMAPT | |
| SCHEMBL1702423 | 0.80 | HSD11B1 (0.57) | RAB9AKMT2AMEN1KDM4EMAPT | |
| SCHEMBL3952453 | 0.80 | ABCB1 (0.58) | RAB9AKMT2AMEN1KDM4EMAPT | |
| SCHEMBL14293042 | 0.78 | TDP1 (0.50) | RAB9AKMT2AMEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108276403-A | A kind of synthetic method of Ka Bolin classes compound | 贵州医科大学 | 2018-07-13 | — | — | CN | disclosed |
| CN-107216328-A | A kind of synthetic method of α Ka Bolin class compounds | 贵州医科大学 | 2017-09-29 | — | — | CN | disclosed |
| US-9011734-B2 | Ligand exchange thermochromic, (LETC), systems | PLEOTINT, L.L.C. (US) | 2015-04-21 | — | — | US | disclosed |
| EP-2082005-B9 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT LLC (US) | 2013-05-22 | — | — | EP | disclosed |
| US-8431045-B2 | Ligand exchange thermochromic systems and high ε ligands for same | PLEOTINT, L.L.C. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120292581-A1 | LIGAND EXCHANGE THERMOCHROMIC SYSTEMS AND HIGH E LIGANDS FOR SAME | PLEOTINT, LLC (US) | 2012-11-22 | — | — | US | disclosed |
| EP-2082005-B1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| US-8182718-B2 | Ligand exchange thermochromic systems and high ε ligands for same | PLEOTINT, L.L.C. (US) | 2012-05-22 | — | — | US | disclosed |
| EP-2436750-A2 | Ligand exchange thermochromic, (LETC), systems | Pleotint, L.L.C. (US) | 2012-04-04 | — | — | EP | disclosed |
| EP-2434000-A2 | Ligand exchange thermochromic, (LETC), systems | Pleotint, L.L.C. (US) | 2012-03-28 | — | — | EP | disclosed |
| US-7538931-B2 | Ligand exchange thermochromic systems containing exchange metals | PLEOTINT, L.L.C. (US) | 2009-05-26 | — | — | US | disclosed |
| US-7525717-B2 | reversible; laminated; transition metal ion coordinated with a high epsilon ligand and a low epsilon ligand; polymer; separator; variable light transmission windows; polyvinyl butyral; nickel or cobalt iodide ligands; diol, triol or polyol ligands | PLEOTINT, L.L.C. (US) | 2009-04-28 | — | — | US | disclosed |
| US-20080105851-A1 | Exhibiting a reversible change in absorbance of electromagnetic radiation as the temperature of the system is reversibly changed; comprising a transition metal ion and a ligand | PLEOTINT, LLC (US) | 2008-05-08 | — | — | US | disclosed |
| US-20080106781-A1 | LIGAND EXCHANGE THERMOCHROMIC SYSTEMS CONTAINING EXCHANGE METALS | PLEOTINT, LLC (US) | 2008-05-08 | — | — | US | disclosed |
| US-20080100902-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, LLC (US) | 2008-05-01 | — | — | US | disclosed |
| US-20080100903-A1 | MULTI-LAYER LIGAND EXCHANGE THERMOCHROMIC SYSTEMS | PLEOTINT, LLC (US) | 2008-05-01 | — | — | US | disclosed |
| WO-2008028128-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, L.L.C. (US) | 2008-03-06 | — | — | WO | disclosed |
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |
| EP-0000816-A1 | Substituted amino-pyridine derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1979-02-21 | — | — | EP | disclosed |