SCHEMBL22944992

SCHEMBL22944992

c1ccc2c3c(ccc2c1)-c1cccc2cccc(c12)N3c1nc(-c2ccc3c(c2)sc2ccccc23)c2ccccc2n1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.34
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 2/20 0.34
HPGD P15428 3/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PDE6D O43924 1/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22944991 0.94 L3MBTL1 (0.34) L3MBTL1ALDH1A1KDM4EHPGDLMNA
SCHEMBL21515463 0.90 ALDH1A1 (0.35) L3MBTL1ALDH1A1KDM4EHPGDLMNA
SCHEMBL21515297 0.88 L3MBTL1 (0.33) L3MBTL1ALDH1A1KDM4EHPGDLMNA
SCHEMBL22945498 0.88 ALDH1A1 (0.33) L3MBTL1ALDH1A1KDM4EHPGDLMNA
SCHEMBL22946023 0.87 ALOX5 (0.32)
SCHEMBL22945035 0.87 PDE6D (0.31) PDE6D
SCHEMBL22945584 0.87 PDE6D (0.36) L3MBTL1ALDH1A1KDM4EHPGDMAPK1
SCHEMBL22944990 0.86 L3MBTL1 (0.32) L3MBTL1ALDH1A1KDM4EHPGDLMNA
SCHEMBL22944796 0.86 PDE6D (0.38) L3MBTL1ALDH1A1KDM4EHPGDMAPK1
SCHEMBL22944987 0.85 ALOX5 (0.32) L3MBTL1ALDH1A1KDM4EHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME DRD1, DRD3, DRD2 L3MBTL1 339/4885ALDH1A1 271/4885KDM4E 1857/4885
US-11812658-B2 Compound and organic light emitting diode comprising same DRD1, DRD3, DRD2 L3MBTL1 339/4885ALDH1A1 271/4885KDM4E 1857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.